Description

2-Fluoro-6-Hydroxy-4-Methylphenylboronic Acid is a specialized organoboron compound that serves as a versatile building block in modern synthetic chemistry. Its value lies in its unique substitution pattern, which allows for selective cross-coupling reactions and the construction of complex molecular architectures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds requiring a fluorinated phenolic scaffold.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, leveraging the fluorine atom for enhanced biological activity and stability.
• Suzuki-Miyaura Cross-Coupling Reactions: Acts as a critical boronic acid coupling partner for forming carbon-carbon bonds in complex organic molecule assembly.
• Ligand and Catalyst Development: Employed in the creation of novel ligands for catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Serves as a monomer or functionalization agent in the development of advanced polymers and electronic materials.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological systems and enzyme activity.

Basic Information

Product Name	2-Fluoro-6-Hydroxy-4-Methylphenylboronic Acid
CAS No.	1803598-06-2
Molecular Formula	C7H8BFO3
Molecular Weight	169.95 g/mol
Synonyms	(2-Fluoro-6-hydroxy-4-methylphenyl)boronic acid; 2-Fluoro-4-methyl-6-hydroxybenzeneboronic acid; 4-Methyl-2-fluoro-6-hydroxybenzeneboronic acid; Boronic acid, B-(2-fluoro-6-hydroxy-4-methylphenyl)-; 1803598-06-2; 2-Fluoro-6-hydroxy-p-tolylboronic acid
EINECS	Contact for details

Quality Control

Every batch of our 2-Fluoro-6-Hydroxy-4-Methylphenylboronic Acid is manufactured under strict quality management systems. We employ advanced analytical techniques, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.