Description

(6-Amino-3-Chloro-2-Fluorophenyl)Boronic Acid is a high-purity, multifunctional boronic acid derivative serving as a critical building block in modern synthetic chemistry. Its value lies in its unique trifunctional scaffold, which enables efficient cross-coupling reactions and the construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, particularly for developing active pharmaceutical ingredients (APIs) and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Material Science: Serves as a monomer or cross-linking agent in the production of specialty polymers, organic electronic materials, and metal-organic frameworks (MOFs).
• Chemical Biology & Proteomics: Employed in the design of molecular probes, enzyme inhibitors, and bioconjugation reagents due to its boronic acid functionality.
• Catalyst Ligand Development: Utilized to create novel ligands for transition metal catalysts used in asymmetric synthesis.
• Academic & Contract Research: A valuable reagent for method development and exploring new synthetic pathways in academic and industrial R&D laboratories.

Basic Information

Product Name	(6-Amino-3-Chloro-2-Fluorophenyl)Boronic Acid
CAS No.	1802430-56-3
Molecular Formula	C6H6BClFNO2
Molecular Weight	189.38 g/mol
Synonyms	2-Amino-5-Chloro-6-Fluorophenylboronic Acid; (2-Amino-5-Chloro-6-Fluorophenyl)boronic Acid; 6-Amino-3-chloro-2-fluorobenzeneboronic Acid; B-(6-Amino-3-chloro-2-fluorophenyl)boronic Acid; 1802430-56-3; AKOS026713023; (6-Amino-3-chloro-2-fluoro-phenyl)boronic acid
EINECS	Contact for details

Quality Control

Our (6-Amino-3-Chloro-2-Fluorophenyl)Boronic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment. We support custom synthesis and can tailor specifications to meet specific project requirements, including compliance with ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.