Description

Gip (3 - 42), Human is a synthetic peptide fragment corresponding to a specific sequence of the gastric inhibitory polypeptide (GIP) hormone. This high-purity reference standard is critical for metabolic and endocrine research, providing a reliable tool for studying GIP receptor interactions and signaling pathways. It is primarily utilized by pharmaceutical R&D teams and academic researchers focused on diabetes, obesity, and metabolic syndrome.

Application

• Biochemical Research: Used as a reference standard in receptor binding assays and signal transduction studies.
• Drug Discovery: Serves as a key reagent for screening and developing novel GIP receptor agonists or antagonists for metabolic diseases.
• Analytical Method Development: Employed as a calibrant for HPLC, LC-MS, and other analytical techniques to quantify GIP-related peptides.
• Antibody Production & Validation: Acts as an immunogen or a standard for the development and testing of specific antibodies in immunoassays (ELISA, RIA).
• Cell-based Assays: Applied in in vitro studies to investigate the physiological effects of GIP on insulin secretion and adipocyte function.

Basic Information

Product Name	Gip (3 - 42), Human
CAS No.	1802086-25-4
Molecular Formula	C191H306N56O58S
Molecular Weight	4299.9 g/mol
Synonyms	Gastric Inhibitory Polypeptide (3-42), human; GIP (3-42); GIP fragment 3-42; Glucose-dependent Insulinotropic Polypeptide (3-42); Tyr-Ala-Glu-Gly-Thr-Phe-Ile-Ser-Asp-Tyr-Ser-Ile-Ala-Met-Asp-Lys-Ile-His-Gln-Gln-Asp-Phe-Val-Asn-Trp-Leu-Leu-Ala-Gln-Lys-Gly-Lys-Lys-Asn-Asp-Trp-Lys-His-Asn-Ile-Thr-Gln; H-Tyr-Ala-Glu-Gly-Thr-Phe-Ile-Ser-Asp-Tyr-Ser-Ile-Ala-Met-Asp-Lys-Ile-His-Gln-Gln-Asp-Phe-Val-Asn-Trp-Leu-Leu-Ala-Gln-Lys-Gly-Lys-Lys-Asn-Asp-Trp-Lys-His-Asn-Ile-Thr-Gln-OH
EINECS	Contact for details

Quality Control

Our Gip (3 - 42), Human is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and MS for identity confirmation, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to minimize moisture uptake. For long-term storage, keep desiccated at -20°C.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Molecular weight confirmed
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0% (by weight)
Water Content (KF)	≤ 5.0%
Acetate Content (HPIC)	≤ 10.0%
Solubility	Soluble in water or dilute acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.