Description

(Arg)-Amyloid β-Protein (1-40) is a synthetic peptide fragment of the amyloid beta protein, a key molecule in Alzheimer's disease research. This high-purity peptide is critical for studying the mechanisms of amyloid aggregation, neurotoxicity, and the development of potential therapeutic interventions. It is an essential research tool for pharmaceutical R&D, academic laboratories, and diagnostic developers focused on neurodegenerative diseases.

Application

• Biochemical Research: Fundamental studies on the aggregation kinetics, structure, and toxicity of amyloid beta peptides.
• Drug Discovery & Screening: Used as a target or reagent in high-throughput assays to identify and validate potential inhibitors of amyloid fibril formation.
• Antibody Development & Validation: Serves as a critical antigen for the production and testing of antibodies used in diagnostic assays and therapeutic research.
• In Vitro & Cell-Based Assays: Employed to model amyloid-induced cytotoxicity and study cellular pathways involved in neurodegeneration.
• Biomarker Studies: Utilized in the development and calibration of analytical methods (e.g., ELISA, MS) for detecting amyloid beta variants in biological samples.
• Reference Standard: Acts as a qualified reference material for quality control and method validation in research and diagnostic kit manufacturing.

Basic Information

Product Name	(Arg)-Amyloid β-Protein (1-40)
CAS No.	1802084-26-9
Molecular Formula	C194H295N55O58S
Molecular Weight	4329.8 g/mol
Synonyms	Amyloid β-Protein (1-40) (Arg); Aβ (1-40) (Arg); β-Amyloid (1-40) (Arg); Amyloid β-Peptide (1-40) (Arg); DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA (Arg); Aβ40 (Arg); Amyloid Precursor Protein 1-40 Fragment (Arg); Alzheimer's Disease Amyloid Peptide (1-40) (Arg)
EINECS	Contact for details

Quality Control

Our (Arg)-Amyloid β-Protein (1-40) is manufactured under stringent conditions to ensure the highest standards of purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and peptide content. We adhere to ISO 9001 quality management principles, and our processes are designed to meet the rigorous demands of pharmaceutical and academic research.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to prevent condensation and hydrolysis. Aliquot into single-use vials to minimize freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Molecular Weight (MS)	4329.8 ± 2 Da
Solubility	Soluble in water or dilute acetic acid
Endotoxin Level	< 1.0 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.