Description

Cys-Gly-Lys-Lys-Gly-Amyloid β-Protein (35-40) is a synthetic peptide fragment corresponding to residues 35-40 of the amyloid beta protein, a key peptide of interest in neurological research. This compound is crucial for studying protein aggregation mechanisms and the molecular pathology associated with neurodegenerative conditions. It is primarily utilized by research institutions and pharmaceutical developers focused on Alzheimer's disease, amyloidosis, and related therapeutic discovery.

Application

• Biomedical Research: Fundamental studies on amyloid beta peptide aggregation kinetics, fibril formation, and structure-activity relationships.
• Drug Discovery & Screening: Serving as a target or reference standard in high-throughput assays to identify potential inhibitors of amyloid aggregation.
• Diagnostic Development: Use as an antigen or calibrator in the development of immunoassays and biosensors for detecting amyloid-related biomarkers.
• Neuroscience Studies: Investigating the cellular toxicity, synaptic dysfunction, and inflammatory responses induced by amyloid beta fragments in model systems.
• Peptide Chemistry & Conjugation: Acting as a building block or template for creating modified peptides, conjugates, or probes for advanced imaging and targeting studies.

Basic Information

Product Name	Cys-Gly-Lys-Lys-Gly-Amyloid β-Protein (35-40)
CAS No.	1802078-24-5
Molecular Formula	C30H53N11O9S
Molecular Weight	743.88 g/mol
Synonyms	Amyloid β-Protein (35-40) fragment; Aβ(35-40); Cys-Gly-Lys-Lys-Gly-Aβ(35-40); H-CGKLVFF-OH; CGKLVFF; CGKKGAβ(35-40); CGKKG-Amyloid β (35-40); CGKKG-Aβ35-40
EINECS	Contact for details

Quality Control

Our peptide products are manufactured under strict quality systems to ensure batch-to-batch consistency and high purity for research applications. Certificates of Analysis (COA) are provided with each batch, detailing purity, identity, and other critical parameters. Quality is verified using advanced analytical techniques including HPLC and Mass Spectrometry to meet the exacting standards required for biomedical research.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Mass spectrum consistent with theoretical molecular weight
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.