Description

Cys-Gly-Lys-Lys-Gly-Amyloid β-Protein (33-40) CAS NO 1802078-23-4 is a synthetic peptide fragment corresponding to a specific sequence of the amyloid beta protein. This compound is of significant value in biochemical and neurological research, particularly for studying protein aggregation mechanisms and the molecular pathology associated with Alzheimer's disease. It is primarily utilized by research institutions, pharmaceutical R&D departments, and diagnostic developers focused on neurodegenerative disorders and peptide-based therapeutic discovery.

Application

• Biochemical Research: Used as a critical reference standard and tool peptide for investigating the aggregation kinetics and structural properties of amyloid beta peptides.
• Drug Discovery & Screening: Serves as a target substrate in high-throughput assays to identify and evaluate potential inhibitors of amyloid beta aggregation.
• Antibody Development & Validation: Employed as an antigen for the production and specificity testing of antibodies targeting specific epitopes within the amyloid beta protein.
• Diagnostic Assay Development: Utilized in the calibration and quality control of immunoassays (e.g., ELISA) designed to detect amyloid beta fragments in biological samples.
• Neuroscience Studies: Applied in cellular and animal model studies to elucidate the neurotoxic effects and signaling pathways triggered by specific amyloid beta domains.
• Peptide Chemistry & Conjugation: Acts as a building block or model compound for developing novel peptide conjugates, probes, or imaging agents.

Basic Information

Product Name	Cys-Gly-Lys-Lys-Gly-Amyloid β-Protein (33-40)
CAS No.	1802078-23-4
Molecular Formula	C38H66N12O11S
Molecular Weight	899.07 g/mol
Synonyms	Cys-Gly-Lys-Lys-Gly-Aβ(33-40); Aβ(33-40) fragment; Amyloid β-Protein (33-40) fragment; Cysteinyl-glycyl-L-lysyl-L-lysyl-glycyl-Amyloid β-Proptide (33-40); CGKKGAβ(33-40); H-CGK-KG-Aβ(33-40)-OH; Aβ33-40 peptide derivative
EINECS	Contact for details

Quality Control

Our peptide products are manufactured and tested under stringent quality management systems. Each batch of Cys-Gly-Lys-Lys-Gly-Amyloid β-Protein (33-40) undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing results for purity (HPLC), molecular weight (MS), and other critical parameters are provided with every shipment to support your research integrity and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (MS)	Consistent with theoretical molecular weight
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Water Content (KF)	≤ 5.0%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.