Description

5-Amino-6-Fluoro-Pyridine-2-Carbonitrile is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound matters because its unique structure, featuring amino, fluoro, and nitrile functional groups on a pyridine core, enables precise molecular design and derivatization. It is critically needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Ligand and Catalyst Development: Serves as a versatile scaffold for constructing complex ligands used in catalytic systems and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the creation of specialty polymers, dyes, and electronic materials requiring specific fluorinated aromatic components.
• Chemical Biology Probes: Utilized as a building block for fluorescent tags, photoaffinity labels, and other molecular probes for biological research.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	5-Amino-6-Fluoro-Pyridine-2-Carbonitrile
CAS No.	1801842-10-3
Molecular Formula	C6H4FN3
Molecular Weight	137.12 g/mol
Synonyms	2-Cyano-5-amino-6-fluoropyridine; 6-Fluoro-5-aminopicolinonitrile; 5-Amino-6-fluoro-2-cyanopyridine; 5-Amino-6-fluoropyridine-2-carbonitrile; 2-Pyridinecarbonitrile, 5-amino-6-fluoro-; 1801842-10-3; 6-Fluoro-5-aminopyridine-2-carbonitrile
EINECS	Contact for details

Quality Control

Our 5-Amino-6-Fluoro-Pyridine-2-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports your R&D and scale-up processes with reliable, high-purity material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.