Description

Benzeneacetamide, α-Amino-3-Fluoro-, Hydrochloride (1:1) is a high-purity fluorinated amino acid derivative, serving as a critical building block in advanced organic synthesis. This compound is valued for its role in introducing specific fluorine-containing motifs into target molecules, which is essential for modulating the physicochemical and biological properties of pharmaceuticals and agrochemicals. It is primarily utilized by research institutions and industrial R&D departments focused on developing novel active ingredients, particularly in medicinal chemistry for drug discovery programs.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of fluorinated active pharmaceutical ingredients (APIs), including potential kinase inhibitors and CNS-targeting drugs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore the impact of fluorine substitution on potency, metabolic stability, and bioavailability.
• Agrochemical Synthesis: Serves as a precursor in the development of new-generation fluorinated pesticides and herbicides with enhanced efficacy and environmental profiles.
• Peptide Modification: Employed to incorporate fluorinated amino acid analogs into peptides, creating tools for biochemical research and potential therapeutic peptides.
• Chemical Biology Probes: Utilized in the synthesis of labeled compounds and molecular probes for studying biological mechanisms and target engagement.
• Custom Synthesis & Contract Manufacturing: A starting material for custom synthesis projects requiring specific, high-value fluorinated chemical architectures.

Basic Information

Product Name	Benzeneacetamide, α-Amino-3-Fluoro-, Hydrochloride (1:1)
CAS No.	1801739-59-2
Molecular Formula	C8H9FN2O·HCl
Molecular Weight	204.63 g/mol (Free base: 168.17 g/mol)
Synonyms	3-Fluoro-DL-phenylglycinamide hydrochloride; (±)-2-Amino-2-(3-fluorophenyl)acetamide hydrochloride; α-Amino-3-fluorobenzeneacetamide hydrochloride; DL-3-Fluorophenylglycinamide hydrochloride; 2-(3-Fluorophenyl)-2-aminoacetamide hydrochloride; 3-Fluoro-α-aminophenylacetamide hydrochloride; (RS)-2-Amino-2-(3-fluorophenyl)acetamide monohydrochloride
EINECS	Contact for details

Quality Control

Our Benzeneacetamide, α-Amino-3-Fluoro-, Hydrochloride (1:1) is manufactured under a strict quality management system. Every batch is subjected to comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting critical parameters such as assay, chiral purity (where applicable), and impurity profiles. We support cGMP compliance for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area%)	≥ 98.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.