Description

(Z)-N-(1-Chloro-1-(2-Cyanophenyl)-3-Oxo-3-(Piperidin-1-Yl)Prop-1-En-2-Yl)Benzamide is a high-purity, advanced pharmaceutical intermediate characterized by its complex molecular architecture featuring a chlorinated enone and benzamide core. This compound matters for its critical role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), enabling the development of targeted therapeutics. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries working on innovative drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the multi-step synthesis of complex drug candidates, particularly in medicinal chemistry research.
• API Synthesis: Used in the development and scale-up of new Active Pharmaceutical Ingredients (APIs), especially those targeting specific enzyme or receptor pathways.
• Chemical Biology Research: Employed as a molecular probe or scaffold in studying biological interactions and mechanisms of action.
• Process Chemistry: Utilized in route scouting and optimization for the efficient, scalable production of target molecules.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services for the pharmaceutical sector.
• Academic Research: Used in university and institutional labs for cutting-edge research in organic synthesis and drug discovery methodologies.

Basic Information

Product Name	(Z)-N-(1-Chloro-1-(2-Cyanophenyl)-3-Oxo-3-(Piperidin-1-Yl)Prop-1-En-2-Yl)Benzamide
CAS No.	1800044-75-0
Molecular Formula	C22H20ClN3O2
Molecular Weight	393.87 g/mol
Synonyms	(Z)-1-Chloro-1-(2-cyanophenyl)-3-oxo-3-(piperidin-1-yl)prop-1-en-2-yl benzamide; Benzamide, N-[(1Z)-1-chloro-1-(2-cyanophenyl)-3-oxo-3-(1-piperidinyl)-1-propen-2-yl]-; (Z)-1-Chloro-1-(2-cyanophenyl)-3-oxo-3-(piperidin-1-yl)prop-1-en-2-yl carboxamide (phenyl substituted); 1800044-75-0; (Z)-enaminone benzamide derivative; Chloro-cyanophenyl-oxo-piperidinyl-propenyl-benzamide
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is analyzed using advanced techniques like HPLC, NMR, and MS to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are available upon request. We adhere to a strict quality management system to ensure batch-to-batch consistency and reliability for your critical research and development processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.