Description

Benzene, 2-Fluoro-1-Iodo-4-(Phenylmethoxy)- is a high-value, multi-functional aromatic building block designed for advanced synthetic chemistry. This compound matters for its unique substitution pattern, offering a reactive iodine handle and a protected phenol group, which enables precise, sequential functionalization in complex molecule assembly. Pharmaceutical researchers and fine chemical manufacturers need it for developing active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials where controlled aromatic substitution is critical.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of functionalized monomers for advanced polymers and liquid crystals.
• Chemical Biology Probes: Useful for tagging and modifying biomolecules due to its reactive halogen and orthogonal protecting group.
• Academic & Industrial R&D: A versatile reagent for method development and exploring new synthetic pathways in organic chemistry.

Basic Information

Product Name	Benzene, 2-Fluoro-1-Iodo-4-(Phenylmethoxy)-
CAS No.	1799824-50-2
Molecular Formula	C13H10FIO
Molecular Weight	328.12 g/mol
Synonyms	2-Fluoro-1-iodo-4-(phenylmethoxy)benzene; 1-Benzyloxy-2-fluoro-4-iodobenzene; 4-(Benzyloxy)-2-fluoro-1-iodobenzene; 2-Fluoro-4-(benzyloxy)iodobenzene; 1-Iodo-2-fluoro-4-(phenylmethoxy)benzene; Benzene, 1-benzyloxy-2-fluoro-4-iodo-; 2-Fluoro-4-iodophenyl benzyl ether
EINECS	Contact for details

Quality Control

Every batch of Benzene, 2-Fluoro-1-Iodo-4-(Phenylmethoxy)- is produced and tested under a strict quality management system. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards and customer-specific requirements. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling should be conducted under appropriate conditions to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Any single impurity ≤ 1.0%; Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.