Description

4-Dechloro-4-(3-Chlorophenyl) Haloperidol Decanoate is a high-purity synthetic intermediate of significant interest in advanced pharmaceutical research and development. This compound is crucial for the synthesis and study of novel neuroleptic agents and their long-acting depot formulations. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on central nervous system (CNS) therapeutics.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of haloperidol analogs and related butyrophenone derivatives.
• Neuroleptic Drug Research: Used in preclinical studies to develop new antipsychotic medications with modified pharmacokinetic profiles.
• Metabolite & Impurity Standard: Serves as a reference standard in analytical chemistry for quality control and regulatory testing of active pharmaceutical ingredients (APIs).
• Long-Acting Injectable (LAI) Formulation Studies: Investigated for the development of decanoate ester prodrugs aimed at sustained drug release.
• Pharmacological Profiling: Employed in receptor binding assays and other in vitro studies to understand structure-activity relationships (SAR).
• Process Chemistry Development: Used for route scouting and optimization in the scale-up synthesis of complex neuroactive compounds.

Basic Information

Item	Details
Product Name	4-Dechloro-4-(3-Chlorophenyl) Haloperidol Decanoate
CAS No.	1797131-50-0
Molecular Formula	C31H41ClFNO3
Molecular Weight	530.11 g/mol
Synonyms	4-Dechloro-4-(3-chlorophenyl)haloperidol decanoate; Haloperidol Decanoate Impurity; 4-(3-Chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]-4-piperidinyl decanoate (dechloro analog); 4-(3-Chlorophenyl)-4-piperidinol, 1-[4-(4-fluorophenyl)-4-oxobutyl]-, decanoate; Butyrophenone derivative intermediate; Decanoic acid, ester with 4-(3-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]-4-piperidinol
EINECS	Contact for details

Quality Control

Our 4-Dechloro-4-(3-Chlorophenyl) Haloperidol Decanoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC, NMR, and MS to confirm identity and purity, ensuring it meets the stringent requirements for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.