Description

n-[[(5S)-3-[4-(4-Morpholinyl)Phenyl]-2-Oxo-5-Oxazolidinyl]Methyl]Acetamide-D3 is a deuterated isotopologue of a key oxazolidinone-based pharmaceutical intermediate. This compound is specifically designed for use in advanced drug metabolism and pharmacokinetic (DMPK) studies, offering enhanced analytical precision. It is primarily utilized by pharmaceutical R&D teams and contract research organizations (CROs) engaged in the development of novel antibacterial agents.

Application

• As a deuterated internal standard for the accurate quantification of its non-deuterated counterpart in bioanalytical methods (LC-MS/MS).
• In metabolic stability studies and tracer experiments to elucidate drug metabolism pathways.
• For use in pharmacokinetic (PK) profiling during preclinical and clinical development stages of new chemical entities.
• As a critical reference material in quality control laboratories for ensuring batch-to-batch consistency of active pharmaceutical ingredients (APIs).
• In research focused on oxazolidinone-class antibiotics, aiding in structural-activity relationship (SAR) studies.

Basic Information

Product Name	n-[[(5S)-3-[4-(4-Morpholinyl)Phenyl]-2-Oxo-5-Oxazolidinyl]Methyl]Acetamide-D3
CAS No.	1795786-92-3
Molecular Formula	C₁₆H₁₈D₃N₃O₄
Molecular Weight	322.37 g/mol
Synonyms	Acetamide, N-[[(5S)-3-[4-(4-morpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]-, 1,1,1-d3-; Deuterated Oxazolidinone Intermediate; (S)-N-((3-(4-Morpholinophenyl)-2-oxooxazolidin-5-yl)methyl)acetamide-d3; Deuterated Linezolid Related Compound D3; Isotopically Labeled Pharmaceutical Intermediate; 1795786-92-3; Deuterated Morpholinophenyl Oxazolidinone
EINECS	Contact for details

Quality Control

Our deuterated compounds are manufactured under strict quality management systems. Each batch is characterized by advanced analytical techniques including NMR, HPLC, and mass spectrometry to confirm chemical identity, isotopic purity (D-enrichment), and chemical purity. Certificates of Analysis (COA) detailing all specifications are provided and available upon request, supporting compliance with GMP and ICH guidelines for pharmaceutical reference standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-enrichment)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.