Description

5-[[(2S)-2-Hydroxypropanoyl]Amino]-2,4,6-Triiodo-1-N,3-n-Bis(1,1,3,3-Tetradeuterio-1,3-Dihydroxypropan-2-Yl)Benzene-1,3-Dicarboxamide is a deuterated derivative of a triiodinated benzene dicarboxamide, designed for advanced research and development applications. This compound is of significant interest due to its incorporation of deuterium atoms, which can be leveraged to study metabolic pathways, enhance stability, or serve as an internal standard in analytical methods. It is primarily utilized by researchers and developers in the pharmaceutical and biotechnology sectors, particularly those focused on contrast agent development, metabolic studies, and analytical chemistry.

Application

• Pharmaceutical Research & Development: As a key intermediate or reference standard in the development of novel X-ray or CT contrast media agents.
• Metabolic and Pharmacokinetic Studies: Utilizing the deuterium label as a stable, non-radioactive tracer to investigate drug metabolism, absorption, and excretion pathways.
• Analytical Chemistry: Serving as a high-purity internal standard for quantitative analysis via Liquid Chromatography-Mass Spectrometry (LC-MS) or other spectroscopic techniques to ensure accuracy and reproducibility.
• Biomedical Imaging Probe Development: Exploration in the synthesis of targeted imaging probes where the iodine atoms provide contrast and the deuterium offers isotopic differentiation.
• Chemical Biology: Use as a specialized tool compound to study protein-ligand interactions or biochemical mechanisms where isotopic labeling is required.
• Process Chemistry & Scale-Up: Supporting route scouting and optimization for the industrial-scale production of related diagnostic compounds.

Basic Information

Product Name	5-[[(2S)-2-Hydroxypropanoyl]Amino]-2,4,6-Triiodo-1-N,3-n-Bis(1,1,3,3-Tetradeuterio-1,3-Dihydroxypropan-2-Yl)Benzene-1,3-Dicarboxamide
CAS No.	1795778-90-3
Molecular Formula	C20H21D8I3N3O8
Molecular Weight	Contact for details
Synonyms	5-[(2S)-2-Hydroxypropanamido]-2,4,6-triiodo-N1,N3-bis[(2S)-1,1,3,3-tetradeuterio-1,3-dihydroxypropan-2-yl]isophthalamide; Deuterated Iopamidol Derivative; 5-[(S)-2-Hydroxypropionylamino]-2,4,6-triiodo-N,N'-bis[(2S)-1,1,3,3-tetradeuterio-1,3-dihydroxyisopropyl]isophthalamide; Iopamidol-d8; (2S)-5-Acetamido-2,4,6-triiodo-N,N'-bis[(2S)-1,1,3,3-tetradeuterio-1,3-dihydroxyisopropyl]isophthalamide; 1795778-90-3; Triiodinated Deuterated Benzene Dicarboxamide
EINECS	Contact for details

Quality Control

Our 5-[[(2S)-2-Hydroxypropanoyl]Amino]-2,4,6-Triiodo-1-N,3-n-Bis(1,1,3,3-Tetradeuterio-1,3-Dihydroxypropan-2-Yl)Benzene-1,3-Dicarboxamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and isotopic enrichment, NMR for structural confirmation, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and impurity profiles to support your research and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider desiccants or an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (D-content, MS)	≥ 98 atom % D
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.