Description

5-Bromo-1,3-Dioxaindane-4-Carbonitrile is a high-value, heterocyclic organic building block featuring a bromine substituent and a nitrile functional group. This compound is critical for advanced organic synthesis, enabling the construction of complex molecular architectures through cross-coupling and cyclization reactions. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the discovery and development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Material Science: Serves as a monomer or functional additive in the research of specialty polymers and advanced organic electronic materials.
• Chemical Synthesis: An essential building block for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and other metal-mediated transformations.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological development and exploration of new chemical spaces.

Basic Information

Product Name	5-Bromo-1,3-Dioxaindane-4-Carbonitrile
CAS No.	1795662-62-2
Molecular Formula	C10H6BrNO2
Molecular Weight	252.07 g/mol
Synonyms	5-Bromo-1,3-dioxaindane-4-carbonitrile; 4-Cyano-5-bromo-1,3-benzodioxole; 5-Bromo-4-cyano-1,3-benzodioxole; 5-Bromo-1,3-benzodioxole-4-carbonitrile; 5-Bromo-4-cyanobenzodioxole; 5-Bromo-4-cyano-1,3-dioxaindane; 5-Bromo-1,3-dioxaindane-4-carbonitrile (CAS 1795662-62-2)
EINECS	Contact for details

Quality Control

Our 5-Bromo-1,3-Dioxaindane-4-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.