Description

Peramivir-13C,15N2 is a stable isotope-labeled analog of the antiviral drug Peramivir, specifically enriched with carbon-13 and nitrogen-15 isotopes. This compound is a critical reference standard and internal standard for the precise quantification and pharmacokinetic studies of Peramivir using advanced analytical techniques like LC-MS/MS. It is primarily required by pharmaceutical R&D laboratories, contract research organizations (CROs), and diagnostic manufacturers engaged in drug development, bioanalytical method validation, and clinical research for influenza treatment.

Application

• Bioanalytical Reference Standard: Serves as a primary standard for calibrating mass spectrometry equipment in quantitative bioanalysis of Peramivir in biological matrices (plasma, serum, urine).
• Pharmacokinetic & Metabolite Studies: Used as an internal standard to ensure accuracy and precision in studies investigating drug absorption, distribution, metabolism, and excretion (ADME).
• Drug Development & Quality Control: Essential for method development and validation in pharmaceutical R&D and manufacturing QC to monitor Peramivir API and finished product quality.
• Clinical Research: Supports clinical trial sample analysis to determine drug concentration levels in patients, ensuring reliable study data.
• Diagnostic Assay Development: Utilized in the development and calibration of in-vitro diagnostic (IVD) tests for therapeutic drug monitoring of antiviral agents.

Basic Information

Product Name	Peramivir-13C,15N2
CAS No.	1794979-37-5
Molecular Formula	C1513CH28N415N2O4
Molecular Weight	~333.4 g/mol (for labeled form)
Synonyms	(1S,2S,3S,4R)-3-[(1S)-1-Acetamido-2-ethylbutyl]-4-[(amino-15N2)carbamoyl]-2-(13C)hydroxycyclopentanecarboxylic acid; Peramivir-13C,15N2; BCX 1812-13C,15N2; RWJ 270201-13C,15N2; Stable Isotope Labeled Peramivir; Peramivir Internal Standard; Peramivir-13C,15N2 (CRM)
EINECS	Contact for details

Quality Control

Our Peramivir-13C,15N2 is manufactured under strict quality control protocols to ensure the highest isotopic and chemical purity for critical analytical applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing isotopic enrichment, chemical purity (by HPLC), and identity confirmation (by NMR and MS). We adhere to relevant guidelines for reference standard materials to ensure reliability and traceability in your analytical workflows.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive); allow the sealed vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥98.0% (chemical purity)
Isotopic Enrichment	≥99 atom % 13C; ≥99 atom % 15N
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.