Description

Paracetamol Dimer Impurity-D6 CAS NO 1794817-30-3 is a deuterium-labeled internal standard used for the precise quantification of paracetamol dimer impurities in pharmaceutical analysis. This high-purity reference material is critical for ensuring the accuracy and reliability of analytical methods, particularly in mass spectrometry. It is an essential tool for pharmaceutical manufacturers, contract research organizations (CROs), and quality control laboratories engaged in method development, validation, and stability studies of paracetamol (acetaminophen) drug substances and products.

Application

• Internal Standard for LC-MS/MS analysis of paracetamol dimer impurities.
• Quantitative method development and validation in pharmaceutical R&D.
• Quality control and batch release testing for paracetamol API manufacturers.
• Stability indicating assay development for impurity profiling.
• Metabolite and degradation product studies in pharmacokinetic research.
• Calibration standard for ensuring regulatory compliance (ICH Q3A/B, FDA, EMA).
• Use in high-purity reference material kits for analytical laboratories.

Basic Information

Product Name	Paracetamol Dimer Impurity-D6
CAS No.	1794817-30-3
Molecular Formula	C16H10D6N2O4
Molecular Weight	294.32 g/mol
Synonyms	Acetaminophen Dimer Impurity-D6; N-(4-Hydroxyphenyl)acetamide Dimer-D6; 4'-Hydroxyacetanilide Dimer-D6; Deuterated Paracetamol Dimer; APAP Dimer-D6; [D6]-Paracetamol Dimer Impurity; N-Acetyl-p-aminophenol Dimer-D6
EINECS	Contact for details

Quality Control

Every batch of Paracetamol Dimer Impurity-D6 is manufactured under strict quality management systems and undergoes comprehensive analytical characterization. Our products are supplied with a detailed Certificate of Analysis (COA) that includes data from NMR (1H, 13C), Mass Spectrometry (HRMS), and HPLC for identity, chemical purity, and isotopic enrichment. We ensure compliance with the stringent requirements for pharmaceutical reference standards and impurity standards as per ICH guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. This compound is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-enrichment)	≥ 98.0 atom % D
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.