Description

3-Amino-6-Bromo-4-(2-Chlorophenyl)-2(1H)-Quinolinone-D5 is a deuterated analog of a complex quinolinone derivative, serving as a critical stable isotope-labeled compound. This product is essential for researchers and developers requiring high-fidelity internal standards for mass spectrometry and other analytical techniques. It is primarily utilized in pharmaceutical R&D, particularly in drug metabolism and pharmacokinetics (DMPK) studies, as well as in the synthesis of novel labeled chemical entities.

Application

• As a stable isotope-labeled internal standard for the quantitative analysis of its non-deuterated counterpart in biological matrices via LC-MS/MS.
• Use in pharmaceutical research for tracing metabolic pathways and conducting accurate pharmacokinetic (PK) studies.
• Application in the development of deuterated drugs, where deuterium incorporation can alter metabolic profiles.
• As a key chemical reference standard in quality control laboratories for method development and validation.
• Employed in academic research involving the mechanistic study of quinolinone-based compounds.
• Potential use as a building block for the synthesis of more complex deuterated molecules in medicinal chemistry.

Basic Information

Product Name	3-Amino-6-Bromo-4-(2-Chlorophenyl)-2(1H)-Quinolinone-D5
CAS No.	1794793-32-0
Molecular Formula	C15H5D5BrClN2O
Molecular Weight	Contact for details
Synonyms	3-Amino-6-bromo-4-(2-chlorophenyl)-2(1H)-quinolinone-d5; 2(1H)-Quinolinone, 3-amino-6-bromo-4-(2-chlorophenyl)-, d5-; Deuterated 3-Amino-6-Bromo-4-(2-Chlorophenyl)quinolin-2(1H)-one; 3-Amino-6-bromo-4-(o-chlorophenyl)-2(1H)-quinolinone-d5; [D5]-3-Amino-6-bromo-4-(2-chlorophenyl)quinolin-2(1H)-one; Labeled ABQ-D5; Stable Isotope Labeled Quinolinone Derivative
EINECS	Contact for details

Quality Control

Our deuterated compounds are produced under controlled conditions to ensure isotopic purity and chemical integrity. Each batch undergoes rigorous analytical testing, including NMR (for deuterium incorporation), HPLC, and MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (e.g., D5, atom % D), chemical purity, and analytical methods is provided with every shipment to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture uptake. Handle and store under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Isotopic Purity (Atom % D)	≥ 98% D5
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.