Description

n-Des[(1-Ethyl-2-Pyrrolidinyl)Methyl]-n-(1-Ethyl-3-Piperidinyl) Amisulpride-D5 is a deuterated analog of an amisulpride derivative, specifically designed for use as an internal standard in analytical chemistry. This high-purity reference material is critical for ensuring the accuracy and reliability of quantitative analyses, particularly in complex biological matrices. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and analytical testing facilities engaged in method development, pharmacokinetic studies, and quality control for neuropsychiatric drug substances and metabolites.

Application

• Internal Standard for LC-MS/MS: Essential for the precise quantification of amisulpride and its metabolites in bioanalytical studies, correcting for instrument variability and matrix effects.
• Pharmaceutical R&D: Supports method development and validation in drug discovery and development pipelines for antipsychotic agents.
• Pharmacokinetic & Metabolism Studies: Enables accurate tracking of drug absorption, distribution, metabolism, and excretion (ADME) in preclinical and clinical research.
• Forensic & Clinical Toxicology: Used in assays to detect and quantify amisulpride in human plasma, serum, or urine for therapeutic drug monitoring or forensic investigations.
• Quality Control & Impurity Profiling: Serves as a critical reference compound in the impurity identification and characterization of bulk drug substances.
• Stable Isotope Labeled Research: Employed in mechanistic studies to trace metabolic pathways using advanced mass spectrometry techniques.

Basic Information

Product Name	n-Des[(1-Ethyl-2-Pyrrolidinyl)Methyl]-n-(1-Ethyl-3-Piperidinyl) Amisulpride-D5
CAS No.	1794786-83-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Amisulpride D5 Derivative; Amisulpride-d5 Metabolite Standard; Deuterated Amisulpride Analog; 4-Amino-N-[(1-ethyl-2-pyrrolidinyl)methyl]-5-(ethylsulfonyl)-2-methoxybenzamide-d5 Derivative; n-Des[(1-Ethylpyrrolidin-2-yl)Methyl]-n-(1-Ethylpiperidin-3-yl) Amisulpride-D5; (1-Ethyl-3-Piperidinyl)-D5 Amisulpride Derivative; Internal Standard for Amisulpride LC-MS
EINECS	Contact for details

Quality Control

Our deuterated reference standards are produced under strict quality management systems. Each batch undergoes comprehensive analytical characterization using techniques including NMR, HPLC, and high-resolution mass spectrometry to confirm structural identity, isotopic purity (D5), and chemical purity. Certificates of Analysis (COA) are provided, detailing batch-specific results for purity, assay, and solvent content, ensuring full traceability and compliance with ISO 17034 guidelines for reference material producers.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C (refrigerated) or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment. Allow the sealed vial to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D5)	≥ 98.0 atom % D
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.