Description

Cyclopentyl 3-[2-Methoxy-4-[m-(Tolyl-D7)Sulfonylcarbamoyl)Benzyl]-1-Methylindol-5-Ylcarbamate is a high-purity, deuterated chemical intermediate designed for advanced research and development. This compound is critical for creating isotopically labeled analogs in pharmaceutical discovery, enabling precise metabolic and pharmacokinetic studies. It is primarily utilized by research institutions and pharmaceutical companies specializing in deuterium chemistry and the development of novel therapeutic agents.

Application

• Pharmaceutical Research & Development: Serves as a key deuterated building block for synthesizing isotopically labeled drug candidates, particularly in oncology and CNS therapeutic areas.
• Metabolic Pathway Tracing: Used in the synthesis of internal standards for Liquid Chromatography-Mass Spectrometry (LC-MS) to study drug metabolism and bioavailability.
• Proteomics & Biomarker Discovery: Employed in the development of chemical probes and affinity tags for target identification and validation studies.
• Preclinical Development: Essential for producing deuterated analogs intended to improve the pharmacokinetic profiles, such as metabolic stability, of lead compounds.
• Contract Research Organizations (CROs): Supplied to CROs conducting specialized deuterium-incorporation chemistry and analytical method development for clients.
• Academic Research: Used in university laboratories investigating novel synthetic methodologies involving sulfonylcarbamoyl and carbamate functionalities.

Basic Information

Product Name	Cyclopentyl 3-[2-Methoxy-4-[m-(Tolyl-D7)Sulfonylcarbamoyl)Benzyl]-1-Methylindol-5-Ylcarbamate
CAS No.	1794760-52-3
Molecular Formula	C31H26D7N3O6S
Molecular Weight	~584.71 g/mol
Synonyms	Cyclopentyl 5-[(2-methoxy-4-[[(3-methylphenyl-d7)sulfonyl]carbamoyl]phenyl)methyl]-1-methyl-1H-indole-3-carboxylate; 1-Methyl-5-[[2-methoxy-4-[[(3-methylphenyl-d7)sulfonyl]carbamoyl]phenyl]methyl]-1H-indol-3-yl cyclopentanecarboxylate; Deuterated Tolyl Sulfonylcarbamoyl Indole Carbamate; CAS 1794760-52-3; m-Tolyl-D7 Sulfonylcarbamoyl Benzyl Indole Carbamate Derivative; Deuterated Pharmaceutical Intermediate 1794760-52-3
EINECS	Contact for details

Quality Control

Every batch of this deuterated intermediate is produced under strict quality control protocols to ensure exceptional purity and isotopic enrichment, critical for sensitive analytical applications. We provide comprehensive Certificates of Analysis (COA) detailing parameters such as chemical purity (by HPLC), isotopic purity (D-content by NMR/MS), and identity confirmation. Our manufacturing aligns with cGMP principles where applicable, supporting its use in regulated research environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept in a desiccated environment. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.