Description

5-[Bis(2-Hydroxyethyl)Amino]-1-(Methyl-D3)-1H-Benzimidazole-2-Butanoic Acid is a high-purity, deuterated benzimidazole derivative designed for advanced research and development applications. This compound is valued for its role as a key synthetic intermediate or analytical standard in the development of novel pharmaceuticals and biochemical tools. It is primarily targeted at R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of deuterated drug candidates, potentially enhancing metabolic stability and pharmacokinetic profiles.
• Metabolic Studies: Used as a stable isotope-labeled internal standard in Liquid Chromatography-Mass Spectrometry (LC-MS) for accurate quantification in bioanalytical assays.
• Proteomics & Biochemistry Research: Acts as a specialized reagent or probe in studying enzyme mechanisms or protein interactions where isotopic labeling is required.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex, high-value organic molecules for research purposes.
• Reference Standard: Provides a certified material for quality control and method validation in analytical laboratories.

Basic Information

Product Name	5-[Bis(2-Hydroxyethyl)Amino]-1-(Methyl-D3)-1H-Benzimidazole-2-Butanoic Acid
CAS No.	1794737-33-9
Molecular Formula	C₁₆H₂₂D₃N₃O₄
Molecular Weight	Approx. 320.39 g/mol
Synonyms	1-(Methyl-d3)-5-[bis(2-hydroxyethyl)amino]-1H-benzimidazole-2-butanoic acid; 5-[Bis(2-hydroxyethyl)amino]-1-(trideuteriomethyl)-1H-benzimidazole-2-butanoic acid; Deuterated Benzimidazole Butanoic Acid Derivative; (Methyl-D3) Benzimidazole Intermediate; CAS 1794737-33-9
EINECS	Contact for details

Quality Control

Our 5-[Bis(2-Hydroxyethyl)Amino]-1-(Methyl-D3)-1H-Benzimidazole-2-Butanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation and deuterium incorporation, to ensure it meets exacting research-grade specifications. A comprehensive Certificate of Analysis (COA) detailing purity, isotopic enrichment, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Deuterium Incorporation (NMR/MS)	≥ 98 atom % D
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.