Description

(3R,4R)-4-Fluorooxolan-3-Ol CAS NO 1793113-98-0 is a high-purity, chiral fluorinated oxolane derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a stereochemically defined scaffold for introducing fluorine and hydroxyl functionalities, which are pivotal for modulating the biological activity and metabolic stability of target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active pharmaceutical ingredients (APIs) and complex fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of fluorinated drug candidates, including protease inhibitors and antiviral agents.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where the fluorinated moiety enhances efficacy and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty fluorinated polymers and advanced organic materials.
• Academic & Industrial R&D: A valuable tool for methodological studies in fluorine chemistry and stereoselective synthesis.

Basic Information

Product Name	(3R,4R)-4-Fluorooxolan-3-Ol
CAS No.	1793113-98-0
Molecular Formula	C4H7FO2
Molecular Weight	106.10 g/mol
Synonyms	(3R,4R)-4-Fluorotetrahydrofuran-3-ol; (3R,4R)-4-Fluorooxolane-3-ol; (3R,4R)-4-Fluoro-THF-3-ol; (3R,4R)-3-Hydroxy-4-fluorotetrahydrofuran; 4-Fluoro-(3R,4R)-tetrahydrofuran-3-ol; 4-Fluoro-(3R,4R)-oxolan-3-ol; (3R,4R)-4-Fluoro-3-hydroxyoxolane
EINECS	Contact for details

Quality Control

Our (3R,4R)-4-Fluorooxolan-3-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with exacting standards for research and process chemistry. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.