Description

Boronic Acid, B-[3-Ethoxy-2-Fluoro-5-(Trifluoromethoxy)Phenyl]- is a high-purity, organoboron building block characterized by its unique trifluoromethoxy and ethoxy substituents. This compound is essential for facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in modern synthetic chemistry for constructing complex molecules. It is a critical intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality reagents for drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, leveraging the stability imparted by the fluorine and trifluoromethoxy groups.
• Material Science Research: Serves as a precursor for creating organic electronic materials, such as those used in OLEDs and semiconductors, due to its ability to form carbon-carbon bonds under mild conditions.
• Chemical Biology & Probe Development: Employed in the design and synthesis of molecular probes and sensors for studying biological processes.
• Cross-Coupling Reactions: Primarily utilized in palladium-catalyzed Suzuki-Miyaura couplings to introduce the 3-ethoxy-2-fluoro-5-(trifluoromethoxy)phenyl moiety into more complex molecular architectures.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences industry.

Basic Information

Product Name	Boronic Acid, B-[3-Ethoxy-2-Fluoro-5-(Trifluoromethoxy)Phenyl]-
CAS No.	1793003-82-3
Molecular Formula	C9H9BF4O4
Molecular Weight	268.0 g/mol (approx.)
Synonyms	[3-Ethoxy-2-fluoro-5-(trifluoromethoxy)phenyl]boronic acid; 2-Fluoro-3-ethoxy-5-(trifluoromethoxy)benzeneboronic acid; (3-Ethoxy-2-fluoro-5-(trifluoromethoxy)phenyl)boronic acid; B-(3-Ethoxy-2-fluoro-5-(trifluoromethoxy)phenyl)boronic acid; 3-Ethoxy-2-fluoro-5-(trifluoromethoxy)phenylboronic acid; Boronic acid, B-[3-ethoxy-2-fluoro-5-(trifluoromethoxy)phenyl]-; CAS 1793003-82-3
EINECS	Contact for details

Quality Control

Our Boronic Acid, B-[3-Ethoxy-2-Fluoro-5-(Trifluoromethoxy)Phenyl]- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring GMP-grade intermediates and research materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.