Description

3-Butoxy-2-Fluoro-4-Methoxyphenylboronic Acid is a specialized organoboron compound used as a key building block in advanced organic synthesis. Its value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Critical building block for synthesizing novel drug candidates, especially those containing complex fluorinated and alkoxy-substituted biaryl motifs.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its specific substitution pattern can influence biological activity.
• Material Science: Serves as a monomer or precursor in the development of organic electronic materials, such as OLEDs and semiconductors.
• Chemical Research: A valuable reagent in academic and industrial R&D for exploring new catalytic cross-coupling methodologies and constructing molecular libraries.
• Ligand Preparation: Can be utilized to synthesize sophisticated ligands for catalysis or metal-organic frameworks (MOFs).

Basic Information

Product Name	3-Butoxy-2-Fluoro-4-Methoxyphenylboronic Acid
CAS No.	1793003-67-4
Molecular Formula	C₁₁H₁₆BFO₄
Molecular Weight	242.05 g/mol
Synonyms	(3-Butoxy-2-fluoro-4-methoxyphenyl)boronic acid; 2-Fluoro-3-butoxy-4-methoxybenzeneboronic acid; 3-Butoxy-2-fluoro-4-methoxybenzeneboronic acid; Boronic acid, B-(3-butoxy-2-fluoro-4-methoxyphenyl)-; 1793003-67-4; (3-Butoxy-2-fluoro-4-methoxyphenyl)boronic acid pinacol ester (common protected form)
EINECS	Contact for details

Quality Control

Our 3-Butoxy-2-Fluoro-4-Methoxyphenylboronic Acid is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for demanding synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality systems are designed to meet the stringent requirements of pharmaceutical and advanced material supply chains.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.