Description

3-Chloro-4-Fluoro-5-(2-Methylpropoxy)Phenylboronic Acid is a high-purity, functionalized phenylboronic acid derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a key coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. It is primarily needed by R&D and production teams in the pharmaceutical and agrochemical industries for developing new active ingredients, as well as by material scientists working on advanced organic electronic materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for targeted therapies.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with specific modes of action.
• Material Science: Serves as a monomer or building block for creating organic semiconductors, liquid crystals, and metal-organic frameworks (MOFs).
• Suzuki-Miyaura Cross-Coupling: Essential reagent for forming carbon-carbon bonds between aryl halides and boronic acids, a cornerstone of modern medicinal chemistry.
• Chemical Research & Development: Employed in academic and industrial labs for exploring new synthetic pathways and creating complex molecular architectures.
• Ligand Synthesis: Can be utilized to develop novel ligands for catalysis and sensor applications.

Basic Information

Product Name	3-Chloro-4-Fluoro-5-(2-Methylpropoxy)Phenylboronic Acid
CAS No.	1793003-51-6
Molecular Formula	C10H13BClFO3
Molecular Weight	245.47 g/mol
Synonyms	[3-Chloro-4-fluoro-5-(2-methylpropoxy)phenyl]boronic acid; 3-Chloro-4-fluoro-5-isobutoxyphenylboronic acid; 5-(Isobutoxy)-3-chloro-4-fluorobenzeneboronic acid; (3-Chloro-4-fluoro-5-isobutoxyphenyl)boronic acid; Boronic acid, B-[3-chloro-4-fluoro-5-[(2-methylpropyl)oxy]phenyl]-; CAS 1793003-51-6
EINECS	Contact for details

Quality Control

Our 3-Chloro-4-Fluoro-5-(2-Methylpropoxy)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistent performance in sensitive coupling reactions. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.