Description

3-Difluoromethyl-4-Nitro-1H-Pyrazole is a high-purity, advanced pharmaceutical intermediate and agrochemical building block. This compound is valued for its unique difluoromethyl and nitro-substituted pyrazole core, which is critical for imparting specific biological activity and metabolic stability in final products. It is primarily utilized by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting enzyme inhibition.
• Agrochemical Synthesis: Serves as a crucial building block for the development of next-generation pesticides, herbicides, and fungicides, leveraging the bioactivity of the difluoromethylpyrazole moiety.
• Chemical Research: Used in academic and industrial R&D for exploring novel heterocyclic chemistry and synthesizing specialized libraries for high-throughput screening.
• Material Science Precursor: Potential use in the synthesis of advanced materials, such as ligands for catalysts or components in specialty polymers.

Basic Information

Product Name	3-Difluoromethyl-4-Nitro-1H-Pyrazole
CAS No.	1789048-54-9
Molecular Formula	C4H3F2N3O2
Molecular Weight	163.08 g/mol
Synonyms	4-Nitro-3-(difluoromethyl)-1H-pyrazole; 3-(Difluoromethyl)-4-nitro-1H-pyrazole; 1H-Pyrazole, 3-(difluoromethyl)-4-nitro-; DFMNP
EINECS	Contact for details

Quality Control

Every batch of 3-Difluoromethyl-4-Nitro-1H-Pyrazole is manufactured under strict quality management systems. Our products undergo rigorous analytical testing to ensure compliance with exacting purity standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.