Description

Benzeneacetonitrile, 4-Bromo-2,5-Difluoro- CAS NO 1785211-45-1 is a high-value, multi-functional aromatic nitrile building block characterized by its bromo and difluoro substitution pattern. This specific substitution makes it a critical intermediate for the synthesis of complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the life sciences sector for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially in the development of fluorine-containing drugs for oncology, CNS, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the bromo and fluoro groups enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for creating specialized aromatic cores used in electronic display technologies and organic light-emitting diodes (OLEDs).
• Polymer Modification: Employed to introduce functional cyano and halogen groups into polymer chains, altering material properties like solubility, thermal stability, and reactivity.
• Cross-Coupling Reactions: The bromo substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to create complex biaryl structures.
• Chemical Research & Development: A versatile reagent in academic and industrial labs for exploring new synthetic methodologies and creating novel chemical entities.

Basic Information

Product Name	Benzeneacetonitrile, 4-Bromo-2,5-Difluoro-
CAS No.	1785211-45-1
Molecular Formula	C8H4BrF2N
Molecular Weight	232.03 g/mol
Synonyms	4-Bromo-2,5-difluorobenzyl cyanide; 2,5-Difluoro-4-bromobenzyl cyanide; (4-Bromo-2,5-difluorophenyl)acetonitrile; 4-Bromo-2,5-difluorophenylacetonitrile; α-(4-Bromo-2,5-difluorophenyl)acetonitrile; 1785211-45-1; 4-Bromo-2,5-difluoro benzeneacetonitrile
EINECS	Contact for details

Quality Control

Our Benzeneacetonitrile, 4-Bromo-2,5-Difluoro- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency essential for sensitive R&D and scale-up processes. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.