Description

(E)-1,3-Difluoro-5-Methoxy-2-(2-Nitrovinyl)Benzene is a high-value, multi-functional aromatic building block characterized by its unique difluoro-methoxy substitution pattern and a reactive nitrovinyl group. This compound matters for its role as a critical intermediate in the synthesis of complex molecules, particularly in pharmaceutical and advanced material research, where its structure enables precise molecular modifications. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in kinase inhibitor and CNS-active molecule research.
• Agrochemical Synthesis: Used in the development of new herbicides and fungicides, leveraging the bioactivity of the difluoro and nitrovinyl motifs.
• Organic Electronics Material Precursor: Serves as a monomer or intermediate in the production of conjugated polymers and small molecules for OLEDs or organic semiconductors.
• Ligand and Catalyst Development: The electron-withdrawing nitrovinyl group makes it useful for constructing complex chelating ligands in catalysis.
• Fluorescent Probe and Dye Synthesis: Acts as a starting material for creating advanced fluorophores and molecular probes used in bioimaging and diagnostics.
• Academic and Contract Research: Essential for methodological studies in organic synthesis, including cross-coupling and cycloaddition reactions.

Basic Information

Product Name	(E)-1,3-Difluoro-5-Methoxy-2-(2-Nitrovinyl)Benzene
CAS No.	1784746-69-5
Molecular Formula	C9H7F2NO3
Molecular Weight	215.15 g/mol
Synonyms	1,3-Difluoro-5-methoxy-2-[(E)-2-nitroethenyl]benzene; 2-(2-Nitrovinyl)-1,3-difluoro-5-methoxybenzene; (E)-2-(2-Nitrovinyl)-1,3-difluoro-5-methoxybenzene; Benzene, 1,3-difluoro-5-methoxy-2-[(E)-2-nitroethenyl]-; (E)-1,3-Difluoro-5-methoxy-2-(2-nitrovinyl)benzene; NSC 868102; MFCD30533366
EINECS	Contact for details

Quality Control

Our (E)-1,3-Difluoro-5-Methoxy-2-(2-Nitrovinyl)Benzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing purity, impurity profile, and physical characteristics are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.