Description

tert-Butyl Methyl(3-Oxocyclobutyl)Carbamate is a high-purity, advanced pharmaceutical intermediate featuring a unique cyclobutanone scaffold. This compound is critical for medicinal chemistry research and development, enabling the synthesis of novel, conformationally constrained bioactive molecules. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing next-generation therapeutics, including protease inhibitors and other small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting proteases and other enzymes.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and lead optimization due to its rigid cyclobutanone core.
• Peptidomimetic Synthesis: Serves as a constrained scaffold to mimic peptide structures, enhancing metabolic stability and bioavailability.
• Fine Chemical Production: Employed in multi-step organic synthesis for creating complex, high-value specialty chemicals.
• Academic & Industrial R&D: Utilized in laboratories for developing new synthetic methodologies and exploring novel chemical spaces.

Basic Information

Product Name	tert-Butyl Methyl(3-Oxocyclobutyl)Carbamate
CAS No.	1783743-14-5
Molecular Formula	C11H19NO3
Molecular Weight	213.27 g/mol
Synonyms	Boc-Methyl-(3-oxocyclobutyl)amine; tert-Butyl N-Methyl-N-(3-oxocyclobutyl)carbamate; Methyl(3-oxocyclobutyl)carbamic acid tert-butyl ester; 1,1-Dimethylethyl methyl(3-oxocyclobutyl)carbamate; N-Boc-N-Methyl-3-aminocyclobutanone; (3-Oxocyclobutyl)(methyl)carbamic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl Methyl(3-Oxocyclobutyl)Carbamate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (typically 15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.