Description

tert-Butyl (3-Fluoro-2-Hydroxypropyl)Carbamate is a specialized fluorinated carbamate building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceuticals and bioactive molecules, where the fluorine atom and protected amine functionality are critical for modulating biological activity and metabolic stability. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries engaged in medicinal chemistry and the synthesis of complex organic targets.

Application

• Key fluorinated intermediate in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates.
• Building block for medicinal chemistry research, particularly in the development of protease inhibitors and kinase modulators.
• Precursor in the preparation of fluorinated amino acid derivatives and peptide mimetics.
• Intermediate for agrochemical research, aiding in the creation of new herbicides or pesticides with enhanced properties.
• Versatile starting material in academic and industrial organic synthesis for introducing protected amine and fluoro-hydroxypropyl motifs.
• Component in the development of molecular probes and diagnostic agents for biochemical research.

Basic Information

Product Name	tert-Butyl (3-Fluoro-2-Hydroxypropyl)Carbamate
CAS No.	1781491-41-5
Molecular Formula	C8H16FNO3
Molecular Weight	193.22 g/mol
Synonyms	Boc-3-Fluoro-2-hydroxypropylamine; N-Boc-3-Fluoro-2-hydroxypropylamine; 1-[(tert-Butoxycarbonyl)amino]-3-fluoro-2-propanol; tert-Butyl N-(3-fluoro-2-hydroxypropyl)carbamate; 3-Fluoro-2-hydroxypropylcarbamic acid tert-butyl ester; (3-Fluoro-2-hydroxypropyl)carbamic acid tert-butyl ester; 2-Hydroxy-3-fluoropropylcarbamic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl (3-Fluoro-2-Hydroxypropyl)Carbamate is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent chemical identity. Certificates of Analysis (COA) with full specification data are provided for every shipment to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using a desiccator or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.