Description

(4,4-Difluorotetrahydro-2H-Pyran-3-Yl)Methanol is a high-value fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in the strategic incorporation of fluorine atoms and a functionalized pyran ring, which are critical for modulating the physicochemical and biological properties of target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, especially in medicinal chemistry programs targeting CNS disorders, metabolic diseases, and anti-infectives.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the difluorinated moiety can enhance bioavailability and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands or organocatalysts used in asymmetric synthesis, leveraging its stereogenic center.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced materials where fluorine incorporation is desired for specific properties like chemical resistance or low surface energy.
• Fluorine Chemistry Building Block: A versatile starting material for further functionalization (e.g., oxidation, substitution) to create a library of more complex fluorinated compounds for screening.

Basic Information

Item	Details
Product Name	(4,4-Difluorotetrahydro-2H-Pyran-3-Yl)Methanol
CAS No.	1781098-50-7
Molecular Formula	C6H10F2O2
Molecular Weight	152.14 g/mol
Synonyms	3-(Hydroxymethyl)-4,4-difluorotetrahydro-2H-pyran; 4,4-Difluoro-3-(hydroxymethyl)tetrahydro-2H-pyran; (4,4-Difluorotetrahydro-2H-pyran-3-yl)methanol; 3-Hydroxymethyl-4,4-difluorotetrahydropyran; 4,4-Difluoro-3-pyranmethanol
EINECS	Contact for details

Quality Control

Our (4,4-Difluorotetrahydro-2H-Pyran-3-Yl)Methanol is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee batch-to-batch consistency and traceability for your R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.