Description

1,4-Dibromo-2-Fluoro-5-Methoxybenzene is a high-purity halogenated aromatic building block of significant interest in advanced organic synthesis. Its value lies in its unique substitution pattern, which provides multiple reactive sites for selective functionalization, making it a versatile intermediate for constructing complex molecular architectures. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing fluorinated and brominated aromatic cores for enhanced bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, where the fluorine and bromine atoms can impart desired biological activity and selectivity.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the creation of organic electronic materials, such as monomers for conductive polymers or liquid crystals, due to its electron-withdrawing halogen substituents.
• Chemical Biology Probes: Useful for labeling and modifying biomolecules in drug discovery and diagnostic assay development.
• Custom Synthesis and Contract Manufacturing: A critical building block for custom synthesis houses serving the life sciences sector, enabling the production of bespoke compounds for client projects.

Basic Information

Product Name	1,4-Dibromo-2-Fluoro-5-Methoxybenzene
CAS No.	1780954-49-5
Molecular Formula	C7H5Br2FO
Molecular Weight	283.92 g/mol
Synonyms	2-Fluoro-1,4-dibromo-5-methoxybenzene; 1,4-Dibromo-2-fluoro-5-methoxybenzene; 5-Methoxy-1,4-dibromo-2-fluorobenzene; Benzene, 1,4-dibromo-2-fluoro-5-methoxy-; 2-Fluoro-5-methoxy-1,4-dibromobenzene
EINECS	Contact for details

Quality Control

Our 1,4-Dibromo-2-Fluoro-5-Methoxybenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.