Description

2-Bromo-3,4-Difluorophenylacetic Acid is a high-purity, multi-functional aromatic building block essential for advanced organic synthesis. This compound is valued for its unique halogenated and fluorinated phenylacetic acid structure, which enables precise molecular modifications in complex chemical pathways. It is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for non-steroidal anti-inflammatory drugs (NSAIDs) and other bioactive molecules.
• Agrochemical Synthesis: Serves as a crucial precursor in the creation of advanced herbicides, fungicides, and pesticides, leveraging the difluoro and bromo substituents for enhanced biological activity.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for transition metal catalysis and in materials science research.
• Fine Chemical Production: Employed in custom synthesis and scale-up processes for producing specialty chemicals with specific fluorinated architectures.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry, including cross-coupling reactions and carboxylate functionalization.

Basic Information

Product Name	2-Bromo-3,4-Difluorophenylacetic Acid
CAS No.	1780785-72-9
Molecular Formula	C8H5BrF2O2
Molecular Weight	251.03 g/mol
Synonyms	2-Bromo-3,4-difluorobenzeneacetic Acid; (2-Bromo-3,4-difluorophenyl)acetic Acid; α-(2-Bromo-3,4-difluorophenyl)acetic Acid; 3,4-Difluoro-2-bromophenylacetic Acid; BDFPA; 1780785-72-9; Benzeneacetic acid, 2-bromo-3,4-difluoro-
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-3,4-Difluorophenylacetic Acid is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.