Description

3-Fluoro-2-Hydroxy-6-Methylanisole is a specialized fluorinated anisole derivative, serving as a high-value synthetic intermediate in advanced organic chemistry. Its molecular structure, featuring both fluorine and hydroxyl substituents, makes it a critical building block for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and oncology.
• Agrochemical Research: Used in the development of next-generation herbicides and pesticides, where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Synthesis: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science: Building block for advanced polymers and liquid crystals, where its aromatic and fluorinated structure contributes to specific material properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring fluorinated aromatic intermediates.

Basic Information

Product Name	3-Fluoro-2-Hydroxy-6-Methylanisole
CAS No.	1780657-91-1
Molecular Formula	C8H9FO2
Molecular Weight	156.16 g/mol
Synonyms	2-Methoxy-3-fluoro-6-methylphenol; 3-Fluoro-2-methoxy-6-methylphenol; 6-Methyl-3-fluoro-2-methoxyphenol; 3-Fluoro-6-methylguaiacol; 1-Fluoro-2-hydroxy-3-methoxy-5-methylbenzene; 2-Hydroxy-3-fluoro-6-methylanisole; 3-Fluoro-2-hydroxy-6-methylmethoxybenzene
EINECS	Contact for details

Quality Control

Every batch of 3-Fluoro-2-Hydroxy-6-Methylanisole is manufactured under strict quality management systems. We provide comprehensive analytical documentation to ensure traceability and consistency for your critical R&D and production processes. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are supplied with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen or argon. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.