Description

tert-Butyl n-(2-Cyanocyclopropyl)Carbamate is a high-purity, advanced pharmaceutical intermediate featuring a unique cyclopropyl nitrile scaffold. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel active pharmaceutical ingredients (APIs) with constrained, three-dimensional architectures. Pharmaceutical R&D and fine chemical synthesis companies need it for developing next-generation therapeutics, particularly in areas like protease inhibitors and other small-molecule drug candidates.

Application

• Pharmaceutical Intermediate: A key synthon for constructing complex molecules in drug discovery and development programs.
• Protease Inhibitor Synthesis: Used in the research and production of inhibitors targeting viral proteases (e.g., HCV, HIV) and other disease-related enzymes.
• Constrained Peptidomimetics: Serves as a rigid, cyclopropyl-based amino acid analog for creating stable peptide mimics with enhanced metabolic stability.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Agrochemical Research: Potential intermediate in the development of novel crop protection agents with unique modes of action.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological studies in organic synthesis and heterocyclic chemistry.

Basic Information

Item	Details
Product Name	tert-Butyl n-(2-Cyanocyclopropyl)Carbamate
CAS No.	1780038-41-6
Molecular Formula	C9H14N2O2
Molecular Weight	182.22 g/mol
Synonyms	tert-Butyl (2-cyanocyclopropyl)carbamate; Boc-2-cyanocyclopropylamine; N-Boc-2-cyanocyclopropylamine; N-(tert-Butoxycarbonyl)-2-cyanocyclopropanamine; 1-((tert-Butoxycarbonyl)amino)-2-cyanocyclopropane; 2-Cyanocyclopropanamine, N-Boc-protected; (2-Cyanocyclopropyl)carbamic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl n-(2-Cyanocyclopropyl)Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Production can be aligned with cGMP guidelines for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.