Description

(R)-3,3'-Bis(3,5-Diisopropylphenyl)-1,1'-Binapthyl-2,2'-Diyl Hydrogenphosphate is a sophisticated chiral phosphoric acid derivative, a key member of the BINOL-based organocatalyst family. This compound is engineered to deliver exceptional enantioselectivity and catalytic efficiency in asymmetric synthesis, a critical requirement for producing high-value chiral intermediates. It is an indispensable tool for R&D and production chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop novel, optically pure compounds.

Application

• Asymmetric Organocatalysis: Serves as a highly efficient Brønsted acid catalyst for a wide range of enantioselective transformations, including Friedel-Crafts alkylations, transfer hydrogenations, and Mannich reactions.
• Pharmaceutical Intermediate Synthesis: Critical for the synthesis of chiral active pharmaceutical ingredients (APIs) where stereochemical purity is paramount for drug efficacy and safety.
• Agrochemical Development: Used in the production of enantiomerically pure herbicides, fungicides, and pesticides to enhance biological activity and reduce environmental impact.
• Chiral Ligand Precursor: Acts as a precursor for the synthesis of complex chiral ligands used in transition metal catalysis.
• Material Science Research: Investigated for the development of chiral functional materials, such as sensors and liquid crystals.
• Academic & Industrial R&D: A valuable reagent for method development and exploring new asymmetric synthetic pathways in research laboratories.

Basic Information

Item	Details
Product Name	(R)-3,3'-Bis(3,5-Diisopropylphenyl)-1,1'-Binapthyl-2,2'-Diyl Hydrogenphosphate
CAS No.	1706459-35-9
Molecular Formula	C50H52O4P
Molecular Weight	739.92 g/mol
Synonyms	(R)-TRIP; (R)-3,3'-Bis(3,5-diisopropylphenyl)-1,1'-binaphthyl-2,2'-diyl phosphate; (R)-3,3'-Bis(3,5-di-iso-propylphenyl)-1,1'-binaphthyl-2,2'-diyl hydrogenphosphate; (R)-Phosphoric acid di-[1,1'-binaphthalene]-2,2'-diyl ester, 3,3'-bis(3,5-diisopropylphenyl)-; Chiral phosphoric acid catalyst (R)-TRIP; (R)-3,3'-Bis(3,5-diisopropylphenyl)-1,1'-binaphthyl-2,2'-diyl dihydrogen phosphate; (R)-BINOL-derived phosphoric acid
EINECS	Contact for details

Quality Control

Every batch of our (R)-3,3'-Bis(3,5-Diisopropylphenyl)-1,1'-Binapthyl-2,2'-Diyl Hydrogenphosphate is manufactured under strict quality management systems. We employ advanced analytical techniques, including HPLC, NMR, and chiral analysis, to ensure high chemical and enantiomeric purity suitable for demanding catalytic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain optimal purity and catalytic activity. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.