Description

(R)-3,3'-Bis(Diphenylphosphanyl)-1,1'-Binapthyl-2,2'-Diyl Hydrogenphosphate is a high-value, chiral phosphine ligand derivative, essential for enabling highly selective and efficient asymmetric catalytic transformations. Its primary value lies in its ability to induce exceptional enantioselectivity in critical bond-forming reactions, directly impacting the purity and yield of advanced chemical intermediates. This compound is indispensable for R&D and production chemists in the pharmaceutical, agrochemical, and fine chemical industries who require precise stereochemical control.

Application

• Asymmetric Hydrogenation: A key ligand for the enantioselective reduction of prochiral olefins, enamines, and ketones in pharmaceutical API synthesis.
• Asymmetric Cross-Coupling: Facilitates stereoselective C-C and C-X bond formations, such as Suzuki-Miyaura and Buchwald-Hartwig amination reactions.
• Chiral Catalyst Preparation: Serves as a precursor or co-ligand for constructing sophisticated transition metal complexes (e.g., with Rh, Ru, Pd).
• Process Chemistry & Scale-Up: Used in the development and optimization of commercial-scale manufacturing routes for optically active compounds.
• Agrochemical Intermediate Synthesis: Enables the production of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Academic & Industrial R&D: A vital tool for methodological development in organic synthesis and catalysis research.

Basic Information

Product Name	(R)-3,3'-Bis(Diphenylphosphanyl)-1,1'-Binapthyl-2,2'-Diyl Hydrogenphosphate
CAS No.	1706439-25-9
Molecular Formula	C44H32O4P3
Molecular Weight	708.63 g/mol
Synonyms	(R)-3,3'-Bis(diphenylphosphino)-1,1'-binaphthyl-2,2'-diyl hydrogenphosphate; (R)-3,3'-Bis(diphenylphosphino)-BINOL phosphate; (R)-BINAP-Phosphate; (R)-BINAP-2,2'-diyl hydrogenphosphate; (R)-BINAP-derived phosphoric acid; Ligand derivative of (R)-BINAP; (R)-H8-BINAP phosphate (related derivative); Contact for additional trade names.
EINECS	Contact for details

Quality Control

Every batch of (R)-3,3'-Bis(Diphenylphosphanyl)-1,1'-Binapthyl-2,2'-Diyl Hydrogenphosphate is manufactured and tested under strict quality management systems to ensure consistent high purity and performance. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, providing full traceability and detailed analytical results from techniques including HPLC, NMR, and chiral analysis.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its sensitivity to oxidation and light, prolonged exposure to air or light should be avoided to maintain stability and efficacy.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.