Description

Potassium Trifluoro((Isopropylamino)Methyl)Borate is a specialized organoboron reagent featuring a trifluoroborate moiety and an isopropylamino-methyl substituent. This compound is valued for its enhanced stability and solubility profile compared to many other boronic acid derivatives, making it a crucial intermediate in advanced synthetic chemistry. It is primarily sought by researchers and manufacturers in the pharmaceutical and agrochemical sectors for applications in cross-coupling reactions, medicinal chemistry, and the development of novel bioactive molecules.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: Acts as a stable, air- and moisture-tolerant organoboron reagent for constructing C-C bonds in complex molecule synthesis.
• Pharmaceutical Intermediate: Serves as a key building block in the research and development of active pharmaceutical ingredients (APIs), particularly for introducing fluorinated or boron-containing motifs.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides that require specific boron-based functional groups.
• Materials Science Research: Employed in the development of organic electronic materials, polymers, and ligands for catalysis.
• Medicinal Chemistry & Drug Discovery: Facilitates the synthesis of compound libraries for high-throughput screening and structure-activity relationship (SAR) studies.
• Process Chemistry & Scale-up: Provides a robust and reliable intermediate for the kilogram-scale production of target molecules under Good Manufacturing Practice (GMP) conditions where applicable.

Basic Information

Product Name	Potassium Trifluoro((Isopropylamino)Methyl)Borate
CAS No.	1705578-42-2
Molecular Formula	C4H9BF3KN
Molecular Weight	178.03 g/mol
Synonyms	Potassium (Isopropylaminomethyl)trifluoroborate; Potassium Trifluoro[(isopropylamino)methyl]borate(1-); (Isopropylaminomethyl)trifluoroborate Potassium Salt; Potassium (Isopropylaminomethyl)trifluoroboranuide; N-Isopropylaminomethyl trifluoroborate potassium salt; Potassium N-Isopropylaminomethyltrifluoroborate; Trifluoro((isopropylamino)methyl)borate Potassium Salt
EINECS	Contact for details

Quality Control

Our Potassium Trifluoro((Isopropylamino)Methyl)Borate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including NMR, HPLC, and elemental analysis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment. We support development and production needs from laboratory to commercial scale, with quality systems adaptable to cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability. Keep away from strong acids and strong bases.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Potassium Content (ICP)	21.5% - 22.5%
Fluorine Content	31.5% - 33.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.