Description

(4-(n-Cyclopropylsulfamoyl)-2,5-Difluorophenyl)Boronic Acid is a sophisticated boronic acid derivative featuring a cyclopropylsulfamoyl moiety and difluorophenyl substitution. This compound is a high-value building block prized for its role in modern synthetic chemistry, particularly in cross-coupling reactions. It is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients. Its specific structure enables the precise construction of complex molecules for advanced applications.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting a range of therapeutic areas.
• Suzuki-Miyaura Cross-Coupling: Serves as a critical organoboron reagent for forming carbon-carbon bonds, enabling the construction of complex biaryl and heterobiaryl structures central to drug discovery.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, where the difluorophenyl and sulfonamide groups can impart desirable biological activity and metabolic stability.
• Material Science Precursor: Employed in the research and development of advanced organic electronic materials, such as those for OLEDs or organic semiconductors.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target engagement.
• Custom Synthesis & Contract Manufacturing: A vital starting material for fine chemical and custom synthesis organizations serving the life sciences sector.

Basic Information

Product Name	(4-(n-Cyclopropylsulfamoyl)-2,5-Difluorophenyl)Boronic Acid
CAS No.	1704121-77-6
Molecular Formula	C9H10BF2NO4S
Molecular Weight	289.06 g/mol
Synonyms	[4-(Cyclopropylsulfamoyl)-2,5-difluorophenyl]boronic acid; 2,5-Difluoro-4-(N-cyclopropylsulfamoyl)phenylboronic acid; 4-(Cyclopropylsulfamoyl)-2,5-difluorobenzeneboronic acid; B-[4-(Cyclopropylsulfamoyl)-2,5-difluorophenyl]boronic acid; (4-(Cyclopropylsulfamoyl)-2,5-difluorophenyl)boronic acid; 1704121-77-6; Boronic acid, B-[4-[[(cyclopropylamino)sulfonyl]-2,5-difluorophenyl]-; AKOS026712293
EINECS	Contact for details

Quality Control

Our (4-(n-Cyclopropylsulfamoyl)-2,5-Difluorophenyl)Boronic Acid is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for research and process development. A comprehensive Certificate of Analysis (COA) detailing purity (typically by HPLC), identity confirmation (NMR, IR), and impurity profiles is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be handled under inert atmosphere (argon/nitrogen) when opening to prevent degradation. For long-term storage, consider storing desiccated at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95% (Typical 97-99%)
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.