Description

(2-Fluoro-4-Methyl-5-(n-Methylsulfamoyl)Phenyl)Boronic Acid is a high-value, multi-functional boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its core value proposition lies in enabling the precise construction of complex molecules through reliable cross-coupling reactions. This advanced intermediate is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for developing new active ingredients. The compound's unique structure, featuring both a boronic acid group and a methylsulfamoyl moiety, makes it a versatile reagent for targeted synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially in oncology and CNS therapeutic areas.
• Agrochemical Research: Used to create advanced active ingredients for crop protection products, leveraging its fluorine and sulfonamide functionalities.
• Material Science: Serves as a monomer or linker in the synthesis of functional polymers and organic electronic materials.
• Chemical Biology & Proteomics: Acts as a versatile handle for bioconjugation and the development of chemical probes and inhibitors.
• Catalyst & Ligand Development: Employed in the design and synthesis of novel organoboron-based catalysts and ligands for asymmetric synthesis.
• Custom Synthesis & Contract Manufacturing: A critical raw material for CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Product Name	(2-Fluoro-4-Methyl-5-(n-Methylsulfamoyl)Phenyl)Boronic Acid
CAS No.	1704121-51-6
Molecular Formula	C8H11BFNO4S
Molecular Weight	247.05 g/mol
Synonyms	5-(Boronic acid)-2-fluoro-4-methyl-N-methylbenzenesulfonamide; [2-Fluoro-4-methyl-5-(N-methylsulfamoyl)phenyl]boronic acid; 2-Fluoro-4-methyl-5-(N-methylsulfamoyl)benzeneboronic acid; B-[2-Fluoro-4-methyl-5-[(methylamino)sulfonyl]phenyl]boronic acid; 5-Borono-2-fluoro-4-methyl-N-methylbenzenesulfonamide; 1704121-51-6; Benzeneboronic acid, 2-fluoro-4-methyl-5-[(methylamino)sulfonyl]-; N-Methyl-2-fluoro-4-methyl-5-boronobenzenesulfonamide
EINECS	Contact for details

Quality Control

Our (2-Fluoro-4-Methyl-5-(n-Methylsulfamoyl)Phenyl)Boronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (argon or nitrogen) when opening the primary container to prevent degradation. For long-term storage, consider desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.