Description

(5-((4-Ethylpiperazin-1-yl)sulfonyl)-2-fluoro-4-methylphenyl)boronic acid is a sophisticated boronic acid derivative featuring a sulfonylated piperazine moiety, making it a valuable building block in modern synthetic chemistry. Its core value lies in its dual functionality, serving as a key intermediate for constructing complex molecules via Suzuki-Miyaura cross-coupling reactions. This compound is primarily needed by researchers and manufacturers in the pharmaceutical industry for the development of new active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and other small-molecule drug discovery programs.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, especially for targeted cancer therapies and central nervous system (CNS) agents.
• Suzuki-Miyaura Cross-Coupling: Serves as the boronic acid coupling partner for the palladium-catalyzed formation of carbon-carbon bonds, enabling the construction of complex biaryl structures.
• Medicinal Chemistry Research: Used extensively in high-throughput screening and structure-activity relationship (SAR) studies to optimize lead compounds.
• Chemical Biology Probes: Employed in the development of molecular probes for studying enzyme function and biological pathways.
• Agrochemical Synthesis: Potential intermediate in the research and development of advanced herbicides and fungicides with novel modes of action.
• Material Science: Can be utilized in the synthesis of organic electronic materials and advanced polymers requiring specific aromatic architectures.

Basic Information

Item	Details
Product Name	(5-((4-Ethylpiperazin-1-yl)sulfonyl)-2-fluoro-4-methylphenyl)boronic Acid
CAS No.	1704121-47-0
Molecular Formula	C14H22BFN2O4S
Molecular Weight	356.21 g/mol
Synonyms	5-[(4-Ethylpiperazin-1-yl)sulfonyl]-2-fluoro-4-methylbenzeneboronic acid; (5-((4-Ethyl-1-piperazinyl)sulfonyl)-2-fluoro-4-methylphenyl)boronic acid; 2-Fluoro-4-methyl-5-(4-ethylpiperazine-1-sulfonyl)phenylboronic acid; B-[5-[(4-Ethyl-1-piperazinyl)sulfonyl]-2-fluoro-4-methylphenyl]boronic acid; Boronic acid, B-[5-[(4-ethyl-1-piperazinyl)sulfonyl]-2-fluoro-4-methylphenyl]-; CAS 1704121-47-0; 1704121-47-0
EINECS	Contact for details

Quality Control

Our (5-((4-Ethylpiperazin-1-yl)sulfonyl)-2-fluoro-4-methylphenyl)boronic acid is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 1.0 %
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.