Description

(2-Fluoro-4-Methyl-5-((4-Methylpiperazin-1-Yl)Sulfonyl)Phenyl)Boronic Acid is a high-value, multi-functional boronic acid derivative designed for advanced synthetic chemistry. This compound is critical for facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex carbon-carbon bonds. It is primarily utilized by pharmaceutical R&D and fine chemical synthesis teams for the development of novel active pharmaceutical ingredients (APIs) and complex organic molecules.

Application

• Pharmaceutical Intermediate Synthesis: A key building block in the research and development of new drug candidates, particularly in oncology and CNS therapeutic areas.
• Suzuki-Miyaura Cross-Coupling Reagent: Enables the efficient formation of biaryl and heterobiaryl structures essential for modern medicinal chemistry.
• Ligand for Catalysis: Can be employed in the development of novel catalysts or as a precursor for catalyst ligands.
• Material Science Research: Used in the synthesis of organic electronic materials, such as polymers for OLEDs or semiconductors.
• Agrochemical Development: Serves as an intermediate in the synthesis of advanced, high-performance crop protection agents.
• Chemical Biology Probes: Useful for creating labeled compounds or probes for studying biological pathways and target engagement.

Basic Information

Product Name	(2-Fluoro-4-Methyl-5-((4-Methylpiperazin-1-Yl)Sulfonyl)Phenyl)Boronic Acid
CAS No.	1704121-45-8
Molecular Formula	C12H18BFN2O4S
Molecular Weight	316.16 g/mol
Synonyms	[2-Fluoro-4-methyl-5-[(4-methylpiperazin-1-yl)sulfonyl]phenyl]boronic acid; 5-Borono-2-fluoro-4-methyl-1-[(4-methylpiperazin-1-yl)sulfonyl]benzene; 2-Fluoro-4-methyl-5-(4-methylpiperazine-1-sulfonyl)phenylboronic acid; Boronic acid, B-[2-fluoro-4-methyl-5-[(4-methyl-1-piperazinyl)sulfonyl]phenyl]-; 1704121-45-8; (2-Fluoro-4-methyl-5-((4-methylpiperazin-1-yl)sulfonyl)phenyl)boronic acid; B-(2-Fluoro-4-methyl-5-((4-methylpiperazin-1-yl)sulfonyl)phenyl)boronic acid
EINECS	Contact for details

Quality Control

Our (2-Fluoro-4-Methyl-5-((4-Methylpiperazin-1-Yl)Sulfonyl)Phenyl)Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC and NMR, to ensure high purity and batch-to-batch consistency suitable for demanding research and development applications. A comprehensive Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its hygroscopic and light-sensitive nature. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.