Description

(5-(N,n-Dimethylsulfamoyl)-2-Fluoro-4-Methylphenyl)Boronic Acid is a high-value, synthetically versatile organoboron compound featuring a dimethylsulfamoyl substituent. This structural complexity makes it a critical advanced pharmaceutical intermediate for constructing novel drug candidates, particularly in medicinal chemistry programs. It is primarily utilized by R&D scientists and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries for Suzuki-Miyaura cross-coupling reactions.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, especially those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science Research: Serves as a precursor for creating functionalized polymers, liquid crystals, and organic electronic materials via palladium-catalyzed coupling.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes, enzyme inhibitors, and bioconjugates for target identification and validation studies.
• Suzuki-Miyaura Cross-Coupling: The primary application is in this palladium-catalyzed reaction to form carbon-carbon bonds, enabling the efficient construction of complex biaryl structures.

Basic Information

Product Name	(5-(N,n-Dimethylsulfamoyl)-2-Fluoro-4-Methylphenyl)Boronic Acid
CAS No.	1704121-40-3
Molecular Formula	C9H13BFNO4S
Molecular Weight	261.08 g/mol
Synonyms	(5-(Dimethylsulfamoyl)-2-fluoro-4-methylphenyl)boronic acid; 2-Fluoro-4-methyl-5-(N,N-dimethylsulfamoyl)phenylboronic acid; B-[5-(Dimethylsulfamoyl)-2-fluoro-4-methylphenyl]boronic acid; 5-(Dimethylsulfamoyl)-2-fluoro-4-methylbenzeneboronic acid; Boronic acid, B-[5-(dimethylsulfamoyl)-2-fluoro-4-methylphenyl]-; 1704121-40-3
EINECS	Contact for details

Quality Control

Our (5-(N,n-Dimethylsulfamoyl)-2-Fluoro-4-Methylphenyl)Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our production adheres to cGMP guidelines where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.