Description

(2-Fluoro-4-Methyl-5-((4-Methylpiperidin-1-Yl)Sulfonyl)Phenyl)Boronic Acid CAS NO 1704121-38-9 is a high-purity, advanced pharmaceutical intermediate featuring a unique sulfonyl piperidine-substituted phenylboronic acid scaffold. This compound is specifically engineered for use in modern cross-coupling reactions, such as the Suzuki-Miyaura reaction, which are critical for constructing complex molecules in drug discovery and development. It is an essential building block for medicinal chemists and process R&D teams in the pharmaceutical and agrochemical industries seeking to synthesize novel active ingredients with targeted properties.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) for small-molecule drug candidates.
• Suzuki-Miyaura Cross-Coupling Reagent: Used to form carbon-carbon bonds, enabling the construction of complex biaryl structures central to many modern therapeutics.
• Medicinal Chemistry & Drug Discovery: Facilitates the rapid exploration of structure-activity relationships (SAR) in lead optimization programs.
• Agrochemical Research: Employed in the development of novel herbicides, fungicides, and insecticides requiring specific aryl-boronic acid motifs.
• Material Science Precursor: Serves as a monomer or functionalization agent in the development of advanced organic electronic materials.
• Chemical Biology Probes: Used to create tagged molecules for studying biological pathways and target engagement.

Basic Information

Product Name	(2-Fluoro-4-Methyl-5-((4-Methylpiperidin-1-Yl)Sulfonyl)Phenyl)Boronic Acid
CAS No.	1704121-38-9
Molecular Formula	C13H19BFO4S
Molecular Weight	313.17 g/mol
Synonyms	[2-Fluoro-4-methyl-5-[(4-methyl-1-piperidyl)sulfonyl]phenyl]boronic acid; B-[2-Fluoro-4-methyl-5-[(4-methyl-1-piperidinyl)sulfonyl]phenyl]boronic acid; 5-((4-Methylpiperidin-1-yl)sulfonyl)-2-fluoro-4-methylphenylboronic acid; 2-Fluoro-4-methyl-5-((4-methylpiperidin-1-yl)sulfonyl)benzeneboronic acid; Boronic acid, B-[2-fluoro-4-methyl-5-[(4-methyl-1-piperidinyl)sulfonyl]phenyl]-; 1704121-38-9; Suzuki Coupling Reagent 1704121-38-9
EINECS	Contact for details

Quality Control

Our (2-Fluoro-4-Methyl-5-((4-Methylpiperidin-1-Yl)Sulfonyl)Phenyl)Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer requirements for pharmaceutical development (GMP standards) or research use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (argon or nitrogen) when possible to maintain stability and purity. Keep the container tightly sealed in a desiccator for long-term storage.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.