Description

(2-Fluoro-4-Methyl-5-(Pyrrolidin-1-Ylsulfonyl)Phenyl)Boronic Acid is a sophisticated aryl boronic acid derivative, a key building block in modern synthetic chemistry. Its value lies in its dual functionality, combining the versatile Suzuki-Miyaura cross-coupling capability of the boronic acid group with the unique electronic and steric properties imparted by the fluorine and pyrrolidine sulfonamide substituents. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries who are developing novel active ingredients, particularly for creating complex biaryl and heterobiaryl structures.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs) via Suzuki-Miyaura cross-coupling reactions.
• Agrochemical Research: Used to construct novel herbicide and pesticide candidates with enhanced biological activity.
• Material Science: Serves as a monomer or building block for creating advanced organic electronic materials and functional polymers.
• Chemical Biology & Proteomics: Employed in the development of molecular probes and enzyme inhibitors targeting sulfonamide-binding domains.
• Ligand Synthesis: Useful for preparing specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Library Synthesis: A valuable reagent for generating diverse compound libraries in high-throughput screening and drug discovery programs.

Basic Information

Product Name	(2-Fluoro-4-Methyl-5-(Pyrrolidin-1-Ylsulfonyl)Phenyl)Boronic Acid
CAS No.	1704121-29-8
Molecular Formula	C11H15BFNO4S
Molecular Weight	287.12 g/mol
Synonyms	[2-Fluoro-4-methyl-5-(pyrrolidin-1-ylsulfonyl)phenyl]boronic acid; 2-Fluoro-4-methyl-5-(1-pyrrolidinylsulfonyl)benzeneboronic acid; 5-Borono-2-fluoro-4-methyl-1-(pyrrolidin-1-ylsulfonyl)benzene; (2-Fluoro-4-methyl-5-(N-pyrrolidinosulfonyl)phenyl)boronic acid; Boronic acid, B-[2-fluoro-4-methyl-5-(1-pyrrolidinylsulfonyl)phenyl]-; CAS 1704121-29-8
EINECS	Contact for details

Quality Control

Our (2-Fluoro-4-Methyl-5-(Pyrrolidin-1-Ylsulfonyl)Phenyl)Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.