Description

(3-Fluoro-4-((4-Methylpiperidin-1-yl)sulfonyl)phenyl)boronic acid is a high-purity, advanced pharmaceutical intermediate featuring a unique sulfonylpiperidine-substituted boronic acid scaffold. This compound is critical for modern medicinal chemistry, specifically enabling the Suzuki-Miyaura cross-coupling reaction, a cornerstone for constructing complex biaryl structures in drug discovery. It is an essential building block for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel small-molecule therapeutics targeting a range of diseases.

Application

• Pharmaceutical Intermediate: A key reagent in the synthesis of active pharmaceutical ingredients (APIs) via palladium-catalyzed cross-coupling reactions.
• Drug Discovery & Medicinal Chemistry: Used extensively in high-throughput screening and lead optimization to create diverse compound libraries with potential biological activity.
• Agrochemical Research: Serves as a building block for developing new crop protection agents and herbicides with novel modes of action.
• Material Science: Potential precursor for creating functionalized polymers or organic electronic materials with specific properties.
• Chemical Biology & Proteomics: Can be utilized in the development of chemical probes and inhibitors for studying enzyme function and protein interactions.
• Academic & Contract Research: Essential for synthetic organic chemistry research in academic institutions and contract research organizations (CROs).

Basic Information

Product Name	(3-Fluoro-4-((4-Methylpiperidin-1-yl)sulfonyl)phenyl)boronic Acid
CAS No.	1704120-89-7
Molecular Formula	C12H17BFNO4S
Molecular Weight	313.15 g/mol
Synonyms	[3-Fluoro-4-[(4-methyl-1-piperidinyl)sulfonyl]phenyl]boronic acid; B-[3-Fluoro-4-[(4-methyl-1-piperidinyl)sulfonyl]phenyl]boronic acid; (3-Fluoro-4-((4-methylpiperidin-1-yl)sulfonyl)phenyl)boronic acid pinacol ester; 4-(4-Methylpiperidine-1-sulfonyl)-3-fluorophenylboronic acid; 1-(2-Fluoro-4-boronophenylsulfonyl)-4-methylpiperidine; 1704120-89-7; Boronic acid, B-[3-fluoro-4-[(4-methyl-1-piperidinyl)sulfonyl]phenyl]-; AKOS026712293
EINECS	Contact for details

Quality Control

Our (3-Fluoro-4-((4-Methylpiperidin-1-yl)sulfonyl)phenyl)boronic acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided to guarantee batch-to-batch consistency and support your regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (argon/nitrogen) when possible to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.