Description

(3-Fluoro-4-(2-(Isopropylamino)Ethoxy)Phenyl)Boronic Acid is a high-value, multifunctional organoboron compound designed for advanced synthetic chemistry. Its core value lies in its dual functionality, serving as a key building block in cross-coupling reactions while offering a protected amine group for further derivatization. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially in kinase inhibitor and CNS-targeted therapeutic research.
• Agrochemical Synthesis: Used to construct complex heterocyclic scaffolds found in modern herbicides, fungicides, and insecticides, leveraging the boronic acid moiety for efficient carbon-carbon bond formation.
• Material Science Research: Serves as a monomer or functionalization agent in the development of organic electronic materials, such as polymers for OLEDs or OFETs, where precise molecular architecture is required.
• Chemical Biology Probes: Employed in the synthesis of bioconjugates and activity-based probes, utilizing the boronic acid group for selective binding and the amine for linker attachment.
• Ligand Development: Acts as a starting material for creating sophisticated bidentate or tridentate ligands used in catalysis and metal-organic frameworks (MOFs).
• Process Chemistry & Scale-up: Provides a reliable and well-defined building block for optimizing synthetic routes from milligram to kilogram scale in process development.

Basic Information

Item	Detail
Product Name	(3-Fluoro-4-(2-(Isopropylamino)Ethoxy)Phenyl)Boronic Acid
CAS No.	1704097-40-4
Molecular Formula	C11H17BFNO3
Molecular Weight	241.07 g/mol
Synonyms	4-(2-((Propan-2-yl)amino)ethoxy)-3-fluorobenzeneboronic acid; 3-Fluoro-4-[2-(isopropylamino)ethoxy]benzeneboronic acid; B-[3-Fluoro-4-[2-(isopropylamino)ethoxy]phenyl]boronic acid; (3-Fluoro-4-(2-(isopropylamino)ethoxy)phenyl)boronic acid pinacol ester (protected form); CAS 1704097-40-4
EINECS	Contact for details

Quality Control

Every batch of our (3-Fluoro-4-(2-(Isopropylamino)Ethoxy)Phenyl)Boronic Acid is manufactured under strict quality management systems. We employ advanced analytical techniques, including HPLC, NMR, and LC-MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Assay	≥ 97%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.