Description

(4-(2-(Cyclohexylamino)Ethoxy)-3-Fluorophenyl)Boronic Acid is a sophisticated boronic acid derivative featuring a cyclohexylaminoethoxy linker and a fluorine substituent on the aromatic ring. This compound is a high-value synthetic intermediate prized for its role in Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in modern organic synthesis. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs) and complex organic molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Suzuki-Miyaura Cross-Coupling: Serves as a critical boronic acid coupling partner for the formation of carbon-carbon bonds between aromatic rings.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and library synthesis for lead optimization.
• Ligand and Catalyst Development: Potential precursor for creating novel ligands or organocatalysts due to its unique functional group combination.
• Material Science Research: Can be incorporated into the synthesis of advanced organic materials, such as polymers or molecular sensors.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.

Basic Information

Product Name	(4-(2-(Cyclohexylamino)Ethoxy)-3-Fluorophenyl)Boronic Acid
CAS No.	1704097-29-9
Molecular Formula	C14H21BFNO3
Molecular Weight	281.13 g/mol
Synonyms	3-Fluoro-4-[2-(cyclohexylamino)ethoxy]benzeneboronic acid; [4-[2-(Cyclohexylamino)ethoxy]-3-fluorophenyl]boronic acid; B-[4-[2-(Cyclohexylamino)ethoxy]-3-fluorophenyl]boronic acid; (4-(2-(Cyclohexylamino)ethoxy)-3-fluorophenyl)boronic acid pinacol ester (common protected form); CAS 1704097-29-9; 4-(2-(Cyclohexylamino)ethoxy)-3-fluorobenzeneboronic acid
EINECS	Contact for details

Quality Control

Our (4-(2-(Cyclohexylamino)Ethoxy)-3-Fluorophenyl)Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95% (Standard Grade)
Assay (NMR)	≥ 97%
Water Content (KF)	≤ 2.0%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.