Description

(4-(n-(tert-Butyl)Sulfamoyl)-2-Fluorophenyl)Boronic Acid is a sophisticated, high-purity organoboron compound designed for advanced synthetic chemistry. This chemical matters as a critical building block in modern pharmaceutical and agrochemical research, enabling the formation of carbon-carbon bonds via Suzuki-Miyaura cross-coupling reactions. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical industry for creating novel active ingredients, as well as by researchers in material science and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those containing sulfonamide and fluorophenyl motifs.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile boronic acid coupling partner for constructing biaryl and heterobiaryl structures central to many active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science: Employed in the creation of organic electronic materials, such as those for OLEDs and organic photovoltaics, due to its functionalized aromatic structure.
• Chemical Biology & Proteomics: Can be utilized as a molecular probe or tag in the study of biological systems and target identification.
• Library Synthesis: Enables the rapid generation of diverse compound libraries for high-throughput screening in drug discovery campaigns.

Basic Information

Product Name	(4-(n-(tert-Butyl)Sulfamoyl)-2-Fluorophenyl)Boronic Acid
CAS No.	1704097-26-6
Molecular Formula	C₁₀H₁₅BFNO₄S
Molecular Weight	287.11 g/mol
Synonyms	4-(N-tert-Butylsulfamoyl)-2-fluorophenylboronic acid; 2-Fluoro-4-[(tert-butylsulfamoyl)]phenylboronic acid; B-[4-[[(1,1-Dimethylethyl)amino]sulfonyl]-2-fluorophenyl]boronic acid; 4-(tert-Butylsulfamoyl)-2-fluorobenzeneboronic acid; (4-(tert-Butylsulfamoyl)-2-fluorophenyl)boronic acid; 1704097-26-6; tert-Butyl-(4-borono-3-fluorophenyl)sulfonamide
EINECS	Contact for details

Quality Control

Our (4-(n-(tert-Butyl)Sulfamoyl)-2-Fluorophenyl)Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency suitable for sensitive research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.