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(4-(n-Cyclopropylsulfamoyl)-2-Fluorophenyl)Boronic Acid CAS NO 1704097-24-4
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CAS No.:1704097-24-4
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
(4-(n-Cyclopropylsulfamoyl)-2-Fluorophenyl)Boronic Acid is a sophisticated organoboron compound featuring a cyclopropylsulfamoyl moiety, serving as a key building block in modern synthetic chemistry. Its core value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex molecular architectures. This high-purity intermediate is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients and advanced materials.
Application
- Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
- Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging the fluorine and sulfonamide groups for enhanced bioactivity and environmental stability.
- Suzuki-Miyaura Cross-Coupling Reactions: Serves as a versatile boronic acid partner for coupling with various aryl/heteroaryl halides to create biaryl and heterobiaryl structures under mild conditions.
- Material Science Research: Employed in the development of organic electronic materials, such as polymers and small molecules for OLEDs and organic photovoltaics.
- Chemical Biology & Probe Development: Utilized as a building block for creating molecular probes and inhibitors to study enzyme function and biological pathways.
- Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds at various scales.
Basic Information
| Item | Detail |
|---|---|
| Product Name | (4-(n-Cyclopropylsulfamoyl)-2-Fluorophenyl)Boronic Acid |
| CAS No. | 1704097-24-4 |
| Molecular Formula | C9H11BFNO4S |
| Molecular Weight | 271.07 g/mol |
| Synonyms | [4-(Cyclopropylsulfamoyl)-2-fluorophenyl]boronic acid; 2-Fluoro-4-(N-cyclopropylsulfamoyl)phenylboronic acid; 4-(Cyclopropylsulfamoyl)-2-fluorobenzeneboronic acid; B-[4-(Cyclopropylsulfamoyl)-2-fluorophenyl]boronic acid; CP-SA-F-PhB(OH)2; 1704097-24-4; Boronic acid, B-[4-[[(cyclopropylamino)sulfonyl]-2-fluorophenyl]- |
| EINECS | Contact for details |
Quality Control
Our (4-(n-Cyclopropylsulfamoyl)-2-Fluorophenyl)Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request to support your regulatory and R&D documentation needs.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when appropriate to maintain stability and purity. Keep away from incompatible materials.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 97.0% |
| Water Content (KF) | ≤ 1.0% |
| Heavy Metals | ≤ 20 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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