Description

(4-(((tert-Butoxycarbonyl)(Cyclohexyl)Amino)Methyl)-2-Fluorophenyl)Boronic Acid is a sophisticated, high-purity boronic acid derivative designed for advanced synthetic chemistry. This compound is a critical building block in modern pharmaceutical research, enabling the precise construction of complex molecules through cross-coupling reactions. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for constructing biaryl structures found in active pharmaceutical ingredients (APIs).
• Drug Discovery & Medicinal Chemistry: Serves as a versatile building block for creating focused libraries and optimizing lead compounds in early-stage research.
• Process Chemistry & Scale-Up: Used in the development and optimization of scalable synthetic routes for candidate drugs.
• Agrochemical Synthesis: Employed in the creation of novel herbicides, fungicides, and insecticides that require specific fluorinated and functionalized aromatic systems.
• Ligand Synthesis for Catalysis: Acts as a starting material for synthesizing novel bidentate or tridentate ligands used in homogeneous catalysis.
• Advanced Materials Research: Utilized in the development of organic electronic materials, such as polymers for OLEDs or OFETs, where precise molecular architecture is crucial.

Basic Information

Product Name	(4-(((tert-Butoxycarbonyl)(Cyclohexyl)Amino)Methyl)-2-Fluorophenyl)Boronic Acid
CAS No.	1704097-11-9
Molecular Formula	C19H29BFNO4
Molecular Weight	365.25 g/mol
Synonyms	(4-(((tert-Butoxycarbonyl)(cyclohexyl)amino)methyl)-2-fluorophenyl)boronic acid; 2-Fluoro-4-((N-(tert-butoxycarbonyl)-N-cyclohexylamino)methyl)phenylboronic acid; Boc-Protected Cyclohexylamino Fluorophenyl Boronic Acid; N-Boc-N-Cyclohexyl-2-fluoro-4-(boronatomethyl)aniline; [4-[[(tert-Butoxycarbonyl)(cyclohexyl)amino]methyl]-2-fluorophenyl]boronic Acid; Boronic acid, B-[4-[[[(1,1-dimethylethoxy)carbonyl](cyclohexyl)amino]methyl]-2-fluorophenyl]-; 1704097-11-9
EINECS	Contact for details

Quality Control

Our (4-(((tert-Butoxycarbonyl)(Cyclohexyl)Amino)Methyl)-2-Fluorophenyl)Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and structural integrity suitable for sensitive coupling reactions. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency, meeting the stringent requirements of pharmaceutical R&D.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., argon or nitrogen) due to its moisture-sensitive and light-sensitive nature. Allow the container to reach room temperature before opening to minimize condensation and moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.